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The lipid-lowering drug fenofibrate combined with si-HOTAIR can effectively inhibit the proliferation of gliomas
BACKGROUND: Fenofibrate is a fibric acid derivative known to have a lipid-lowering effect. Although fenofibrate-induced peroxisome proliferator-activated receptor alpha (PPARα) transcription activation has been shown to play an important role in the malignant progression of gliomas, the underlying m...
Autores principales: | Zhu, Wei, Zhao, Hongyang, Xu, Fenfen, Huang, Bin, Dai, Xiaojing, Sun, Jikui, Nyalali, Alphonce M. K., Zhang, Kailiang, Ni, Shilei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173837/ https://www.ncbi.nlm.nih.gov/pubmed/34082742 http://dx.doi.org/10.1186/s12885-021-08417-z |
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