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Atg7 deficiency in microglia drives an altered transcriptomic profile associated with an impaired neuroinflammatory response
Microglia, resident immunocompetent cells of the central nervous system, can display a range of reaction states and thereby exhibit distinct biological functions across development, adulthood and under disease conditions. Distinct gene expression profiles are reported to define each of these microgl...
Autores principales: | Friess, Lara, Cheray, Mathilde, Keane, Lily, Grabert, Kathleen, Joseph, Bertrand |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173846/ https://www.ncbi.nlm.nih.gov/pubmed/34082793 http://dx.doi.org/10.1186/s13041-021-00794-7 |
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