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The heterogeneous human memory CCR6+ T helper-17 populations differ in T-bet and cytokine expression but all activate synovial fibroblasts in an IFNγ-independent manner

BACKGROUND: Chronic synovial inflammation is an important hallmark of inflammatory arthritis, but the cells and mechanisms involved are incompletely understood. Previously, we have shown that CCR6+ memory T-helper (memTh) cells and synovial fibroblasts (SF) activate each other in a pro-inflammatory...

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Detalles Bibliográficos
Autores principales:	Dankers, Wendy, den Braanker, Hannah, Paulissen, Sandra M. J., van Hamburg, Jan Piet, Davelaar, Nadine, Colin, Edgar M., Lubberts, Erik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173960/ https://www.ncbi.nlm.nih.gov/pubmed/34082814 http://dx.doi.org/10.1186/s13075-021-02532-9

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