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Examining the interactions scorpion venom peptides (HP1090, Meucin-13, and Meucin-18) with the receptor binding domain of the coronavirus spike protein to design a mutated therapeutic peptide

The spike protein of SARS-CoV-2 (Severe Acute Respiratory Syndrome coronavirus 2) interacts with the ACE2 receptor in human cells and starts the infection of COVID-19 disease. Given the importance of spike protein's interaction with ACE2 receptor, we selected some antiviral peptides of venom sc...

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Detalles Bibliográficos
Autores principales: Mahnam, Karim, Lotfi, Maryam, Shapoorabadi, Farzaneh Ahmadi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8174010/
https://www.ncbi.nlm.nih.gov/pubmed/34119951
http://dx.doi.org/10.1016/j.jmgm.2021.107952