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Interneuron Dysfunction in a New Mouse Model of SCN1A GEFS+

Advances in genome sequencing have identified over 1300 mutations in the SCN1A sodium channel gene that result in genetic epilepsies. However, it still remains unclear how most individual mutations within SCN1A result in seizures. A previous study has shown that the K1270T (KT) mutation, linked to g...

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Detalles Bibliográficos
Autores principales:	Das, Antara, Zhu, Bingyao, Xie, Yunyao, Zeng, Lisha, Pham, An T., Neumann, Jonathan C., Safrina, Olga, Benavides, Daniel R., MacGregor, Grant R., Schutte, Soleil S., Hunt, Robert F., O’Dowd, Diane K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Society for Neuroscience 2021
Materias:	Research Article: New Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8174035/ https://www.ncbi.nlm.nih.gov/pubmed/33658306 http://dx.doi.org/10.1523/ENEURO.0394-20.2021

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