AdipoRon Attenuates Inflammation and Impairment of Cardiac Function Associated With Cardiopulmonary Bypass–Induced Systemic Inflammatory Response Syndrome

BACKGROUND: Cardiac surgery using cardiopulmonary bypass (CPB) frequently provokes a systemic inflammatory response syndrome, which is triggered by TLR4 (Toll‐like receptor 4) and TNF‐α (tumor necrosis factor α) signaling. Here, we investigated whether the adiponectin receptor 1 and 2 agonist AdipoR...

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Detalles Bibliográficos
Autores principales: Jenke, Alexander, Yazdanyar, Mariam, Miyahara, Shunsuke, Chekhoeva, Agunda, Immohr, Moritz Benjamin, Kistner, Julia, Boeken, Udo, Lichtenberg, Artur, Akhyari, Payam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8174216/
https://www.ncbi.nlm.nih.gov/pubmed/33666100
http://dx.doi.org/10.1161/JAHA.120.018097

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