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Sex and Race‐Ethnic Disparities in Door‐to‐CT Time in Acute Ischemic Stroke: The Florida Stroke Registry

BACKGROUND: Less than 40% of acute stroke patients have computed tomography (CT) imaging performed within 25 minutes of hospital arrival. We aimed to examine the race‐ethnic and sex differences in door‐to‐CT (DTCT) ≤25 minutes in the FSR (Florida Stroke Registry). METHODS AND RESULTS: Data were coll...

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Autores principales: Polineni, Sai P., Perez, Enmanuel J., Wang, Kefeng, Gutierrez, Carolina M., Walker, Jeffrey, Foster, Dianne, Dong, Chuanhui, Asdaghi, Negar, Romano, Jose G., Sacco, Ralph L., Rundek, Tatjana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8174374/
https://www.ncbi.nlm.nih.gov/pubmed/33787282
http://dx.doi.org/10.1161/JAHA.120.017543
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author Polineni, Sai P.
Perez, Enmanuel J.
Wang, Kefeng
Gutierrez, Carolina M.
Walker, Jeffrey
Foster, Dianne
Dong, Chuanhui
Asdaghi, Negar
Romano, Jose G.
Sacco, Ralph L.
Rundek, Tatjana
author_facet Polineni, Sai P.
Perez, Enmanuel J.
Wang, Kefeng
Gutierrez, Carolina M.
Walker, Jeffrey
Foster, Dianne
Dong, Chuanhui
Asdaghi, Negar
Romano, Jose G.
Sacco, Ralph L.
Rundek, Tatjana
author_sort Polineni, Sai P.
collection PubMed
description BACKGROUND: Less than 40% of acute stroke patients have computed tomography (CT) imaging performed within 25 minutes of hospital arrival. We aimed to examine the race‐ethnic and sex differences in door‐to‐CT (DTCT) ≤25 minutes in the FSR (Florida Stroke Registry). METHODS AND RESULTS: Data were collected from 2010 to 2018 for 63 265 patients with acute ischemic stroke from the FSR and secondary analysis was performed on 15 877 patients with intravenous tissue plasminogen activator‐treated ischemic stroke. Generalized estimating equation models were used to determine predictors of DTCT ≤25. DTCT ≤25 was achieved in 56% of cases of suspected acute stroke, improving from 36% in 2010 to 72% in 2018. Women (odds ratio [OR], 0.90; 95% CI, 0.87–0.93) and Black (OR, 0.88; CI, 0.84–0.94) patients who had strokes were less likely, and Hispanic patients more likely (OR, 1.07; CI, 1.01–1.14), to achieve DTCT ≤25. In a secondary analysis among intravenous tissue plasminogen activator‐treated patients, 81% of patients achieved DTCT ≤25. In this subgroup, women were less likely to receive DTCT ≤25 (0.85, 0.77–0.94) whereas no significant differences were observed by race or ethnicity. CONCLUSIONS: In the FSR, there was considerable improvement in acute stroke care metric DTCT ≤25 in 2018 in comparison to 2010. However, sex and race‐ethnic disparities persist and require further efforts to improve performance and reduce these disparities.
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spelling pubmed-81743742021-06-11 Sex and Race‐Ethnic Disparities in Door‐to‐CT Time in Acute Ischemic Stroke: The Florida Stroke Registry Polineni, Sai P. Perez, Enmanuel J. Wang, Kefeng Gutierrez, Carolina M. Walker, Jeffrey Foster, Dianne Dong, Chuanhui Asdaghi, Negar Romano, Jose G. Sacco, Ralph L. Rundek, Tatjana J Am Heart Assoc Original Research BACKGROUND: Less than 40% of acute stroke patients have computed tomography (CT) imaging performed within 25 minutes of hospital arrival. We aimed to examine the race‐ethnic and sex differences in door‐to‐CT (DTCT) ≤25 minutes in the FSR (Florida Stroke Registry). METHODS AND RESULTS: Data were collected from 2010 to 2018 for 63 265 patients with acute ischemic stroke from the FSR and secondary analysis was performed on 15 877 patients with intravenous tissue plasminogen activator‐treated ischemic stroke. Generalized estimating equation models were used to determine predictors of DTCT ≤25. DTCT ≤25 was achieved in 56% of cases of suspected acute stroke, improving from 36% in 2010 to 72% in 2018. Women (odds ratio [OR], 0.90; 95% CI, 0.87–0.93) and Black (OR, 0.88; CI, 0.84–0.94) patients who had strokes were less likely, and Hispanic patients more likely (OR, 1.07; CI, 1.01–1.14), to achieve DTCT ≤25. In a secondary analysis among intravenous tissue plasminogen activator‐treated patients, 81% of patients achieved DTCT ≤25. In this subgroup, women were less likely to receive DTCT ≤25 (0.85, 0.77–0.94) whereas no significant differences were observed by race or ethnicity. CONCLUSIONS: In the FSR, there was considerable improvement in acute stroke care metric DTCT ≤25 in 2018 in comparison to 2010. However, sex and race‐ethnic disparities persist and require further efforts to improve performance and reduce these disparities. John Wiley and Sons Inc. 2021-03-31 /pmc/articles/PMC8174374/ /pubmed/33787282 http://dx.doi.org/10.1161/JAHA.120.017543 Text en © 2021 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Original Research
Polineni, Sai P.
Perez, Enmanuel J.
Wang, Kefeng
Gutierrez, Carolina M.
Walker, Jeffrey
Foster, Dianne
Dong, Chuanhui
Asdaghi, Negar
Romano, Jose G.
Sacco, Ralph L.
Rundek, Tatjana
Sex and Race‐Ethnic Disparities in Door‐to‐CT Time in Acute Ischemic Stroke: The Florida Stroke Registry
title Sex and Race‐Ethnic Disparities in Door‐to‐CT Time in Acute Ischemic Stroke: The Florida Stroke Registry
title_full Sex and Race‐Ethnic Disparities in Door‐to‐CT Time in Acute Ischemic Stroke: The Florida Stroke Registry
title_fullStr Sex and Race‐Ethnic Disparities in Door‐to‐CT Time in Acute Ischemic Stroke: The Florida Stroke Registry
title_full_unstemmed Sex and Race‐Ethnic Disparities in Door‐to‐CT Time in Acute Ischemic Stroke: The Florida Stroke Registry
title_short Sex and Race‐Ethnic Disparities in Door‐to‐CT Time in Acute Ischemic Stroke: The Florida Stroke Registry
title_sort sex and race‐ethnic disparities in door‐to‐ct time in acute ischemic stroke: the florida stroke registry
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8174374/
https://www.ncbi.nlm.nih.gov/pubmed/33787282
http://dx.doi.org/10.1161/JAHA.120.017543
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