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Epigenomic regulation of human T-cell leukemia virus by chromatin-insulator CTCF

Human T-cell leukemia virus type 1 (HTLV-1) is a retrovirus that causes an aggressive T-cell malignancy and a variety of inflammatory conditions. The integrated provirus includes a single binding site for the epigenomic insulator, CCCTC-binding protein (CTCF), but its function remains unclear. In th...

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Detalles Bibliográficos
Autores principales: Cheng, Xiaogang, Joseph, Ancy, Castro, Victor, Chen-Liaw, Alice, Skidmore, Zachary, Ueno, Takaharu, Fujisawa, Jun-ichi, Rauch, Daniel A., Challen, Grant A., Martinez, Michael P., Green, Patrick, Griffith, Malachi, Payton, Jacqueline E., Edwards, John R., Ratner, Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8174705/
https://www.ncbi.nlm.nih.gov/pubmed/34019588
http://dx.doi.org/10.1371/journal.ppat.1009577