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Successful contact tracing systems for COVID-19 rely on effective quarantine and isolation

Models of contact tracing often over-simplify the effects of quarantine and isolation on disease transmission. We develop a model that allows us to investigate the importance of these factors in reducing the effective reproduction number. We show that the reduction in onward transmission during quar...

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Autores principales: James, A., Plank, M. J., Hendy, S., Binny, R., Lustig, A., Steyn, N., Nesdale, A., Verrall, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8174731/
https://www.ncbi.nlm.nih.gov/pubmed/34081709
http://dx.doi.org/10.1371/journal.pone.0252499
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author James, A.
Plank, M. J.
Hendy, S.
Binny, R.
Lustig, A.
Steyn, N.
Nesdale, A.
Verrall, A.
author_facet James, A.
Plank, M. J.
Hendy, S.
Binny, R.
Lustig, A.
Steyn, N.
Nesdale, A.
Verrall, A.
author_sort James, A.
collection PubMed
description Models of contact tracing often over-simplify the effects of quarantine and isolation on disease transmission. We develop a model that allows us to investigate the importance of these factors in reducing the effective reproduction number. We show that the reduction in onward transmission during quarantine and isolation has a bigger effect than tracing coverage on the reproduction number. We also show that intuitively reasonable contact tracing performance indicators, such as the proportion of contacts quarantined before symptom onset, are often not well correlated with the reproduction number. We conclude that provision of support systems to enable people to quarantine and isolate effectively is crucial to the success of contact tracing.
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spelling pubmed-81747312021-06-14 Successful contact tracing systems for COVID-19 rely on effective quarantine and isolation James, A. Plank, M. J. Hendy, S. Binny, R. Lustig, A. Steyn, N. Nesdale, A. Verrall, A. PLoS One Research Article Models of contact tracing often over-simplify the effects of quarantine and isolation on disease transmission. We develop a model that allows us to investigate the importance of these factors in reducing the effective reproduction number. We show that the reduction in onward transmission during quarantine and isolation has a bigger effect than tracing coverage on the reproduction number. We also show that intuitively reasonable contact tracing performance indicators, such as the proportion of contacts quarantined before symptom onset, are often not well correlated with the reproduction number. We conclude that provision of support systems to enable people to quarantine and isolate effectively is crucial to the success of contact tracing. Public Library of Science 2021-06-03 /pmc/articles/PMC8174731/ /pubmed/34081709 http://dx.doi.org/10.1371/journal.pone.0252499 Text en © 2021 James et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
James, A.
Plank, M. J.
Hendy, S.
Binny, R.
Lustig, A.
Steyn, N.
Nesdale, A.
Verrall, A.
Successful contact tracing systems for COVID-19 rely on effective quarantine and isolation
title Successful contact tracing systems for COVID-19 rely on effective quarantine and isolation
title_full Successful contact tracing systems for COVID-19 rely on effective quarantine and isolation
title_fullStr Successful contact tracing systems for COVID-19 rely on effective quarantine and isolation
title_full_unstemmed Successful contact tracing systems for COVID-19 rely on effective quarantine and isolation
title_short Successful contact tracing systems for COVID-19 rely on effective quarantine and isolation
title_sort successful contact tracing systems for covid-19 rely on effective quarantine and isolation
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8174731/
https://www.ncbi.nlm.nih.gov/pubmed/34081709
http://dx.doi.org/10.1371/journal.pone.0252499
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