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Relationship between amyloid and tau levels and its impact on tau spreading

PURPOSE: Previous studies have shown that Aβ-amyloid (Aβ) likely promotes tau to spread beyond the medial temporal lobe. However, the Aβ levels necessary for tau to spread in the neocortex is still unclear. METHODS: Four hundred sixty-six participants underwent tau imaging with [18F]MK6420 and Aβ im...

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Detalles Bibliográficos
Autores principales: Doré, Vincent, Krishnadas, Natasha, Bourgeat, Pierrick, Huang, Kun, Li, Shenpeng, Burnham, Samantha, Masters, Colin L., Fripp, Jurgen, Villemagne, Victor L., Rowe, Christopher C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175299/
https://www.ncbi.nlm.nih.gov/pubmed/33495928
http://dx.doi.org/10.1007/s00259-021-05191-9