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Exploring the role of non-pharmaceutical interventions (NPIs) in flattening the Greek COVID-19 epidemic curve

Due to the COVID-19 pandemic originating in China in December 2019, apart from the grave concerns on the exponentially increasing casualties, the affected countries are called to deal with severe repercussions in all aspects of everyday life, from economic recession to national and international mov...

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Autores principales: Mavragani, Amaryllis, Gkillas, Konstantinos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175358/
https://www.ncbi.nlm.nih.gov/pubmed/34083549
http://dx.doi.org/10.1038/s41598-021-90293-5
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author Mavragani, Amaryllis
Gkillas, Konstantinos
author_facet Mavragani, Amaryllis
Gkillas, Konstantinos
author_sort Mavragani, Amaryllis
collection PubMed
description Due to the COVID-19 pandemic originating in China in December 2019, apart from the grave concerns on the exponentially increasing casualties, the affected countries are called to deal with severe repercussions in all aspects of everyday life, from economic recession to national and international movement restrictions. Several regions managed to handle the pandemic more successfully than others in terms of life loss, while ongoing heated debates as to the right course of action for battling COVID-19 have divided the academic community as well as public opinion. To this direction, in this paper, an autoregressive COVID-19 prediction model with heterogeneous explanatory variables for Greece is proposed, taking past COVID-19 data, non-pharmaceutical interventions (NPIs), and Google query data as independent variables, from the day of the first confirmed case—February 26th—to the day before the announcement for the quarantine measures’ softening—April 24th. The analysis indicates that the early measures taken by the Greek officials positively affected the flattening of the epidemic curve, with Greece having recorded significantly decreased COVID-19 casualties per million population and managing to stay on the low side of the deaths over cases spectrum. In specific, the prediction model identifies the 7-day lag that is needed in order for the measures’ results to actually show, i.e., the optimal time-intervention framework for managing the disease’s spread, while our analysis also indicates an appropriate point during the disease spread where restrictive measures should be applied. Present results have significant implications for effective policy making and in the designing of the NPIs, as the second wave of COVID-19 is expected in fall 2020, and such multidisciplinary analyses are crucial in order to understand the evolution of the Daily Deaths to Daily Cases ratio along with its determinants as soon as possible, for the assessment of the respective domestic health authorities’ policy interventions as well as for the timely health resources allocation.
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spelling pubmed-81753582021-06-04 Exploring the role of non-pharmaceutical interventions (NPIs) in flattening the Greek COVID-19 epidemic curve Mavragani, Amaryllis Gkillas, Konstantinos Sci Rep Article Due to the COVID-19 pandemic originating in China in December 2019, apart from the grave concerns on the exponentially increasing casualties, the affected countries are called to deal with severe repercussions in all aspects of everyday life, from economic recession to national and international movement restrictions. Several regions managed to handle the pandemic more successfully than others in terms of life loss, while ongoing heated debates as to the right course of action for battling COVID-19 have divided the academic community as well as public opinion. To this direction, in this paper, an autoregressive COVID-19 prediction model with heterogeneous explanatory variables for Greece is proposed, taking past COVID-19 data, non-pharmaceutical interventions (NPIs), and Google query data as independent variables, from the day of the first confirmed case—February 26th—to the day before the announcement for the quarantine measures’ softening—April 24th. The analysis indicates that the early measures taken by the Greek officials positively affected the flattening of the epidemic curve, with Greece having recorded significantly decreased COVID-19 casualties per million population and managing to stay on the low side of the deaths over cases spectrum. In specific, the prediction model identifies the 7-day lag that is needed in order for the measures’ results to actually show, i.e., the optimal time-intervention framework for managing the disease’s spread, while our analysis also indicates an appropriate point during the disease spread where restrictive measures should be applied. Present results have significant implications for effective policy making and in the designing of the NPIs, as the second wave of COVID-19 is expected in fall 2020, and such multidisciplinary analyses are crucial in order to understand the evolution of the Daily Deaths to Daily Cases ratio along with its determinants as soon as possible, for the assessment of the respective domestic health authorities’ policy interventions as well as for the timely health resources allocation. Nature Publishing Group UK 2021-06-03 /pmc/articles/PMC8175358/ /pubmed/34083549 http://dx.doi.org/10.1038/s41598-021-90293-5 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Mavragani, Amaryllis
Gkillas, Konstantinos
Exploring the role of non-pharmaceutical interventions (NPIs) in flattening the Greek COVID-19 epidemic curve
title Exploring the role of non-pharmaceutical interventions (NPIs) in flattening the Greek COVID-19 epidemic curve
title_full Exploring the role of non-pharmaceutical interventions (NPIs) in flattening the Greek COVID-19 epidemic curve
title_fullStr Exploring the role of non-pharmaceutical interventions (NPIs) in flattening the Greek COVID-19 epidemic curve
title_full_unstemmed Exploring the role of non-pharmaceutical interventions (NPIs) in flattening the Greek COVID-19 epidemic curve
title_short Exploring the role of non-pharmaceutical interventions (NPIs) in flattening the Greek COVID-19 epidemic curve
title_sort exploring the role of non-pharmaceutical interventions (npis) in flattening the greek covid-19 epidemic curve
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175358/
https://www.ncbi.nlm.nih.gov/pubmed/34083549
http://dx.doi.org/10.1038/s41598-021-90293-5
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