Exosome loaded immunomodulatory biomaterials alleviate local immune response in immunocompetent diabetic mice post islet xenotransplantation

Foreign body response (FBR) to biomaterials compromises the function of implants and leads to medical complications. Here, we report a hybrid alginate microcapsule (AlgXO) that attenuated the immune response after implantation, through releasing exosomes derived from human Umbilical Cord Mesenchymal...

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Detalles Bibliográficos
Autores principales: Mohammadi, M. Rezaa, Rodriguez, Samuel Mathew, Luong, Jennifer Cam, Li, Shiri, Cao, Rui, Alshetaiwi, Hamad, Lau, Hien, Davtyan, Hayk, Jones, Mathew Blurton, Jafari, Mahtab, Kessenbrock, Kai, Villalta, S. Armando, de Vos, Paul, Zhao, Weian, Lakey, Jonathan R. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175379/
https://www.ncbi.nlm.nih.gov/pubmed/34083739
http://dx.doi.org/10.1038/s42003-021-02229-4

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