Sar1b mutant mice recapitulate gastrointestinal abnormalities associated with chylomicron retention disease

Chylomicron retention disease (CRD) is an autosomal recessive disorder associated with biallelic Sar1b mutations leading to defects in intracellular chylomicron (CM) trafficking and secretion. To date, a direct cause-effect relationship between CRD and Sar1b mutation has not been established, but ge...

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Detalles Bibliográficos
Autores principales: Auclair, Nickolas, Sané, Alain T., Ahmarani, Lena, Patey, Nathalie, Beaulieu, Jean-François, Peretti, Noel, Spahis, Schohraya, Levy, Emile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175419/
https://www.ncbi.nlm.nih.gov/pubmed/33964306
http://dx.doi.org/10.1016/j.jlr.2021.100085

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