Crystal structure of dopamine D1 receptor in complex with G protein and a non-catechol agonist

Dopamine D1 receptor (D1R) is an important drug target implicated in many psychiatric and neurological disorders. Selective agonism of D1R are sought to be the therapeutic strategy for these disorders. Most selective D1R agonists share a dopamine-like catechol moiety in their molecular structure, an...

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Detalles Bibliográficos
Autores principales: Sun, Bingfa, Feng, Dan, Chu, Matthew Ling-Hon, Fish, Inbar, Lovera, Silvia, Sands, Zara A., Kelm, Sebastian, Valade, Anne, Wood, Martyn, Ceska, Tom, Kobilka, Tong Sun, Lebon, Florence, Kobilka, Brian K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175458/
https://www.ncbi.nlm.nih.gov/pubmed/34083522
http://dx.doi.org/10.1038/s41467-021-23519-9

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