Loss of Gap Junction Delta-2 (GJD2) gene orthologs leads to refractive error in zebrafish

Myopia is the most common developmental disorder of juvenile eyes, and it has become an increasing cause of severe visual impairment. The GJD2 locus has been consistently associated with myopia in multiple independent genome-wide association studies. However, despite the strong genetic evidence, lit...

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Detalles Bibliográficos
Autores principales: Quint, Wim H., Tadema, Kirke C. D., de Vrieze, Erik, Lukowicz, Rachel M., Broekman, Sanne, Winkelman, Beerend H. J., Hoevenaars, Melanie, de Gruiter, H. Martijn, van Wijk, Erwin, Schaeffel, Frank, Meester-Smoor, Magda, Miller, Adam C., Willemsen, Rob, Klaver, Caroline C. W., Iglesias, Adriana I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175550/
https://www.ncbi.nlm.nih.gov/pubmed/34083742
http://dx.doi.org/10.1038/s42003-021-02185-z

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