Identification of potential chemical compounds enhancing generation of enucleated cells from immortalized human erythroid cell lines

Immortalized erythroid cell lines are expected to be a promising source of ex vivo manufactured red blood cells (RBCs), however the induction of enucleation in these cell lines is inefficient at present. We utilized an imaging-based high-throughput system to identify chemical compounds that trigger...

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Detalles Bibliográficos
Autores principales: Soboleva, Svetlana, Kurita, Ryo, Ek, Fredrik, Åkerstrand, Hugo, Silvério-Alves, Rita, Olsson, Roger, Nakamura, Yukio, Miharada, Kenichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175573/
https://www.ncbi.nlm.nih.gov/pubmed/34083702
http://dx.doi.org/10.1038/s42003-021-02202-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175573/
https://www.ncbi.nlm.nih.gov/pubmed/34083702
http://dx.doi.org/10.1038/s42003-021-02202-1

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