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Identification of potential chemical compounds enhancing generation of enucleated cells from immortalized human erythroid cell lines
Immortalized erythroid cell lines are expected to be a promising source of ex vivo manufactured red blood cells (RBCs), however the induction of enucleation in these cell lines is inefficient at present. We utilized an imaging-based high-throughput system to identify chemical compounds that trigger...
Autores principales: | Soboleva, Svetlana, Kurita, Ryo, Ek, Fredrik, Åkerstrand, Hugo, Silvério-Alves, Rita, Olsson, Roger, Nakamura, Yukio, Miharada, Kenichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175573/ https://www.ncbi.nlm.nih.gov/pubmed/34083702 http://dx.doi.org/10.1038/s42003-021-02202-1 |
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