Transmembrane adaptor protein PAG is a mediator of PD-1 inhibitory signaling in human T cells

The inhibitory receptor PD-1 is expressed on T cells to inhibit select functions when ligated. The complete signaling mechanism downstream of PD-1 has yet to be uncovered. Here, we discovered phosphoprotein associated with glycosphingolipid-enriched microdomains 1 (PAG) is phosphorylated following P...

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Detalles Bibliográficos
Autores principales: Strazza, Marianne, Azoulay-Alfaguter, Inbar, Peled, Michael, Adam, Kieran, Mor, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175585/
https://www.ncbi.nlm.nih.gov/pubmed/34083754
http://dx.doi.org/10.1038/s42003-021-02225-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175585/
https://www.ncbi.nlm.nih.gov/pubmed/34083754
http://dx.doi.org/10.1038/s42003-021-02225-8

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