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Transmembrane adaptor protein PAG is a mediator of PD-1 inhibitory signaling in human T cells
The inhibitory receptor PD-1 is expressed on T cells to inhibit select functions when ligated. The complete signaling mechanism downstream of PD-1 has yet to be uncovered. Here, we discovered phosphoprotein associated with glycosphingolipid-enriched microdomains 1 (PAG) is phosphorylated following P...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175585/ https://www.ncbi.nlm.nih.gov/pubmed/34083754 http://dx.doi.org/10.1038/s42003-021-02225-8 |