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Connectivity adaptations in dopaminergic systems define the brain maturity of investors
Investment decisions rely on perceptions from external stimuli along with the integration of inner brain-body signals, all of which are shaped by experience. As experience is capable of molding both the structure and function of the human brain, we have used a novel neuroimaging connectomic-genetic...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175592/ https://www.ncbi.nlm.nih.gov/pubmed/34083626 http://dx.doi.org/10.1038/s41598-021-91227-x |
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author | Ortiz-Teran, Elena Diez, Ibai Sepulcre, Jorge Lopez-Pascual, Joaquin Ortiz, Tomas |
author_facet | Ortiz-Teran, Elena Diez, Ibai Sepulcre, Jorge Lopez-Pascual, Joaquin Ortiz, Tomas |
author_sort | Ortiz-Teran, Elena |
collection | PubMed |
description | Investment decisions rely on perceptions from external stimuli along with the integration of inner brain-body signals, all of which are shaped by experience. As experience is capable of molding both the structure and function of the human brain, we have used a novel neuroimaging connectomic-genetic approach to investigate the influence of investment work experience on brain anatomy. We found that senior investors display higher gray matter volume and increased structural brain connectivity in dopamine-related pathways, as well as a set of genes functionally associated with adrenaline and noradrenaline biosynthesis (SLC6A3, TH and SLC18A2), which is seemingly involved in reward processing and bodily stress responses during financial trading. These results suggest the key role of catecholamines in the way senior investors harness their emotions while raising bodily awareness as they grow in investment maturity. |
format | Online Article Text |
id | pubmed-8175592 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-81755922021-06-07 Connectivity adaptations in dopaminergic systems define the brain maturity of investors Ortiz-Teran, Elena Diez, Ibai Sepulcre, Jorge Lopez-Pascual, Joaquin Ortiz, Tomas Sci Rep Article Investment decisions rely on perceptions from external stimuli along with the integration of inner brain-body signals, all of which are shaped by experience. As experience is capable of molding both the structure and function of the human brain, we have used a novel neuroimaging connectomic-genetic approach to investigate the influence of investment work experience on brain anatomy. We found that senior investors display higher gray matter volume and increased structural brain connectivity in dopamine-related pathways, as well as a set of genes functionally associated with adrenaline and noradrenaline biosynthesis (SLC6A3, TH and SLC18A2), which is seemingly involved in reward processing and bodily stress responses during financial trading. These results suggest the key role of catecholamines in the way senior investors harness their emotions while raising bodily awareness as they grow in investment maturity. Nature Publishing Group UK 2021-06-03 /pmc/articles/PMC8175592/ /pubmed/34083626 http://dx.doi.org/10.1038/s41598-021-91227-x Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Ortiz-Teran, Elena Diez, Ibai Sepulcre, Jorge Lopez-Pascual, Joaquin Ortiz, Tomas Connectivity adaptations in dopaminergic systems define the brain maturity of investors |
title | Connectivity adaptations in dopaminergic systems define the brain maturity of investors |
title_full | Connectivity adaptations in dopaminergic systems define the brain maturity of investors |
title_fullStr | Connectivity adaptations in dopaminergic systems define the brain maturity of investors |
title_full_unstemmed | Connectivity adaptations in dopaminergic systems define the brain maturity of investors |
title_short | Connectivity adaptations in dopaminergic systems define the brain maturity of investors |
title_sort | connectivity adaptations in dopaminergic systems define the brain maturity of investors |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175592/ https://www.ncbi.nlm.nih.gov/pubmed/34083626 http://dx.doi.org/10.1038/s41598-021-91227-x |
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