Evaluation of Intra-Articular Amikacin Administration in an Equine Non-inflammatory Joint Model to Identify Effective Bactericidal Concentrations While Minimizing Cytotoxicity

Septic arthritis causes significant morbidity and mortality in veterinary and human clinical practice and is increasingly complicated by multidrug-resistant infections. Intra-articular (IA) antibiotic administration achieves high local drug concentrations but is considered off-label usage, and appro...

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Detalles Bibliográficos
Autores principales: Pezzanite, Lynn, Chow, Lyndah, Hendrickson, Dean, Gustafson, Daniel L., Russell Moore, A, Stoneback, Jason, Griffenhagen, Gregg M., Piquini, Gabriella, Phillips, Jennifer, Lunghofer, Paul, Dow, Steven, Goodrich, Laurie R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Veterinary Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175670/
https://www.ncbi.nlm.nih.gov/pubmed/34095281
http://dx.doi.org/10.3389/fvets.2021.676774

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