Establishment of an integrated automated embryonic manipulation system for producing genetically modified mice

Genetically modified mice are commonly used in biologic, medical, and drug discovery research, but conventional microinjection methods used for genetic modification require extensive training and practical experience. Here we present a fully automated system for microinjection into the pronucleus to...

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Detalles Bibliográficos
Autores principales: Eto, Tomoo, Ueda, Hiroki, Ito, Ryoji, Takahashi, Tsukasa, Watanabe, Toshiaki, Goto, Motohito, Sotomaru, Yusuke, Tanaka, Nobuaki, Takahashi, Riichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175685/
https://www.ncbi.nlm.nih.gov/pubmed/34083640
http://dx.doi.org/10.1038/s41598-021-91148-9

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