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GABA(A) Alpha 2,3 Modulation Improves Select Phenotypes in a Mouse Model of Fragile X Syndrome

Fragile X syndrome (FXS) is the most common cause of inherited intellectual disability. FXS is caused by functional loss of the Fragile X Protein (FXP), also known as Fragile X Mental Retardation Protein (FMRP). In humans and animal models, loss of FXP leads to sensory hypersensitivity, increased su...

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Detalles Bibliográficos
Autores principales: Schaefer, Tori L., Ashworth, Amy A., Tiwari, Durgesh, Tomasek, Madison P., Parkins, Emma V., White, Angela R., Snider, Andrew, Davenport, Matthew H., Grainger, Lindsay M., Becker, Robert A., Robinson, Chandler K., Mukherjee, Rishav, Williams, Michael T., Gibson, Jay R., Huber, Kimberly M., Gross, Christina, Erickson, Craig A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175776/
https://www.ncbi.nlm.nih.gov/pubmed/34093287
http://dx.doi.org/10.3389/fpsyt.2021.678090

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