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GABA(A) Alpha 2,3 Modulation Improves Select Phenotypes in a Mouse Model of Fragile X Syndrome
Fragile X syndrome (FXS) is the most common cause of inherited intellectual disability. FXS is caused by functional loss of the Fragile X Protein (FXP), also known as Fragile X Mental Retardation Protein (FMRP). In humans and animal models, loss of FXP leads to sensory hypersensitivity, increased su...
Autores principales: | Schaefer, Tori L., Ashworth, Amy A., Tiwari, Durgesh, Tomasek, Madison P., Parkins, Emma V., White, Angela R., Snider, Andrew, Davenport, Matthew H., Grainger, Lindsay M., Becker, Robert A., Robinson, Chandler K., Mukherjee, Rishav, Williams, Michael T., Gibson, Jay R., Huber, Kimberly M., Gross, Christina, Erickson, Craig A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175776/ https://www.ncbi.nlm.nih.gov/pubmed/34093287 http://dx.doi.org/10.3389/fpsyt.2021.678090 |
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