Cargando…

Multiple Molecular Mechanisms to Overcome Multidrug Resistance in Cancer by Natural Secondary Metabolites

Plant secondary metabolites (SMs) common natural occurrences and the significantly lower toxicities of many SM have led to the approaching development and use of these compounds as effective pharmaceutical agents; especially in cancer therapy. A combination of two or three of plant secondary metabol...

Descripción completa

Detalles Bibliográficos
Autores principales:	El-Readi, Mahmoud Zaki, Al-Abd, Ahmed M., Althubiti, Mohammad A., Almaimani, Riyad A., Al-Amoodi, Hiba Saeed, Ashour, Mohamed Lotfy, Wink, Michael, Eid, Safaa Yehia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8176113/ https://www.ncbi.nlm.nih.gov/pubmed/34093189 http://dx.doi.org/10.3389/fphar.2021.658513

Ejemplares similares

Fallopia japonica, a Natural Modulator, Can Overcome Multidrug Resistance in Cancer Cells
por: Eid, Safaa Yehia, et al.
Publicado: (2015)

Overexpression of Inducible Nitric Oxide Synthase in Allergic and Nonallergic Nasal Polyp
por: Sadek, Ahmed Adel, et al.
Publicado: (2019)

Antioxidative and Anti-Inflammatory Protective Effects of Fucoxanthin against Paracetamol-Induced Hepatotoxicity in Rats
por: Koshak, Maimonah Fuad, et al.
Publicado: (2023)

Secondary Metabolites from Plants Inhibiting ABC Transporters and Reversing Resistance of Cancer Cells and Microbes to Cytotoxic and Antimicrobial Agents
por: Wink, Michael, et al.
Publicado: (2012)

The use of the nutritional supplements during the covid-19 outbreak in Saudi Arabia: A cross-sectional study
por: Hafiz, Nada Mohammed, et al.
Publicado: (2023)

Liver Injury in Favipiravir-Treated COVID-19 Patients: Retrospective Single-Center Cohort Study
por: Almutairi, Amal Oweid, et al.
Publicado: (2023)

Cymbopogon citratus and Citral Overcome Doxorubicin Resistance in Cancer Cells via Modulating the Drug’s Metabolism, Toxicity, and Multidrug Transporters
por: Mukhtar, Mohammed Hasan, et al.
Publicado: (2023)

Patterns of acute poisoning for children during outbreak of Corona virus in Makkah region Saudi Arabia
por: Althobaiti, Bashayer Mohammed, et al.
Publicado: (2023)

In Vivo and In Vitro Enhanced Tumoricidal Effects of Metformin, Active Vitamin D(3), and 5-Fluorouracil Triple Therapy against Colon Cancer by Modulating the PI3K/Akt/PTEN/mTOR Network
por: Almaimani, Riyad Adnan, et al.
Publicado: (2022)

Development of Transdermal Oleogel Containing Olmesartan Medoxomil: Statistical Optimization and Pharmacological Evaluation
por: El-Dahmy, Rania Moataz, et al.
Publicado: (2023)

Chrysanthemum indicum and Chrysanthemum morifolium: Chemical Composition of Their Essential Oils and Their Potential Use as Natural Preservatives with Antimicrobial and Antioxidant Activities
por: Youssef, Fadia S., et al.
Publicado: (2020)

Investigation of Hyperlipidemia Associated with Increased Levels of Oxidized Low-Density Lipoproteins and 8-Hydroxy-2´-Deoxyguanosine
por: Babakr, Abdullatif, et al.
Publicado: (2023)

Potential Predictors of Poor Prognosis among Severe COVID-19 Patients: A Single-Center Study
por: Ghaith, Mazen M., et al.
Publicado: (2021)

Tamoxifen and the PI3K Inhibitor: LY294002 Synergistically Induce Apoptosis and Cell Cycle Arrest in Breast Cancer MCF-7 Cells
por: Abdallah, Mohamed E., et al.
Publicado: (2020)

Anti-infective and cytotoxic properties of Bupleurum marginatum
por: Ashour, Mohamed L, et al.
Publicado: (2014)

Is redox signaling a feasible target for overcoming multidrug resistance in cancer chemotherapy?
por: Polimeni, Manuela, et al.
Publicado: (2014)

In Vitro Anticancer and Antibacterial Activities of the Essential Oil of Forsskal’s Basil Growing in Extreme Environmental Conditions
por: Bader, Ammar, et al.
Publicado: (2023)

A Danshensu-Tetramethylpyrazine Conjugate DT-010 Overcomes Multidrug Resistance in Human Breast Cancer
por: Zhou, Xinhua, et al.
Publicado: (2019)

Gibberellin derivative GA-13315 overcomes multidrug resistance in breast cancer by up-regulating BMP6 expression
por: Luo, Xianqiang, et al.
Publicado: (2022)

Capsaicin and Piperine Can Overcome Multidrug Resistance in Cancer Cells to Doxorubicin
por: Li, Hanmei, et al.
Publicado: (2018)

Enhanced anti-cancer effects of oestrogen and progesterone co-therapy against colorectal cancer in males
por: Mahbub, Amani A., et al.
Publicado: (2022)

Sage, Salvia officinalis L., Constituents, Hepatoprotective Activity, and Cytotoxicity Evaluations of the Essential Oils Obtained from Fresh and Differently Timed Dried Herbs: A Comparative Analysis
por: Mohammed, Hamdoon A., et al.
Publicado: (2021)

Editorial: Considering plant metabolites and their synthetic derivatives as candidates for the development of drugs against multidrug resistant (MDR) tumors
por: Rijo, Patricia, et al.
Publicado: (2022)

Reversal of Multidrug Resistance in Human Colon Cancer and Human Leukemia Cells by Three Plant Extracts and Their Major Secondary Metabolites
por: Zhou, Jun-Xian, et al.
Publicado: (2018)

Ginsenoside Rg5 overcomes chemotherapeutic multidrug resistance mediated by ABCB1 transporter: in vitro and in vivo study
por: Feng, Sen-Ling, et al.
Publicado: (2020)

Betulinic Acid Exerts Cytotoxic Activity Against Multidrug-Resistant Tumor Cells via Targeting Autocrine Motility Factor Receptor (AMFR)
por: Saeed, Mohamed E. M., et al.
Publicado: (2018)

Efficacy-Based Perspective to Overcome Reduced Opioid Analgesia of Advanced Painful Diabetic Neuropathy in Rats
por: Balogh, Mihály, et al.
Publicado: (2019)

A machine-learning guided method for predicting add-on and switch in secondary data sources: A case study on anti-seizure medications in Danish registries
por: Breitenstein, Peter Suhr, et al.
Publicado: (2022)

Syzygium aqueum: A Polyphenol- Rich Leaf Extract Exhibits Antioxidant, Hepatoprotective, Pain-Killing and Anti-inflammatory Activities in Animal Models
por: Sobeh, Mansour, et al.
Publicado: (2018)

Isolation and Characterization of Two New Secondary Metabolites From Quercus incana and Their Antidepressant- and Anxiolytic-Like Potential
por: Sarwar, Rizwana, et al.
Publicado: (2018)

Rhus coriaria L. (Sumac) Evokes Endothelium-Dependent Vasorelaxation of Rat Aorta: Involvement of the cAMP and cGMP Pathways
por: Anwar, Mohammad A., et al.
Publicado: (2018)

Editorial: Application of Plant Secondary Metabolites to Pain Neuromodulation
por: Singla, Rajeev K., et al.
Publicado: (2021)

Secondary Metabolites of Osmanthus fragrans: Metabolism and Medicinal Value
por: Fu, Chen-Chen, et al.
Publicado: (2022)

Combating and overcoming drug resistance in cancer
por: Price, Douglas K.
Publicado: (2014)

Overcoming Obstacles to Drug Repositioning in Japan
por: Nishimura, Yuhei, et al.
Publicado: (2017)

Molecular Insights Into SARS COV-2 Interaction With Cardiovascular Disease: Role of RAAS and MAPK Signaling
por: Wehbe, Zena, et al.
Publicado: (2020)

Linezolid resistance in multidrug-resistant mycobacterium tuberculosis: A systematic review and meta-analysis
por: Azimi, Taher, et al.
Publicado: (2022)

Wound Healing Properties of Jasione montana Extracts and Their Main Secondary Metabolites
por: Juszczak, Aleksandra Maria, et al.
Publicado: (2022)

Editorial: Application of plant secondary metabolites to pain neuromodulation, volume II
por: Singla, Rajeev K., et al.
Publicado: (2022)

Editorial: Application of plant secondary metabolites to pain neuromodulation, volume III
por: Singla, Rajeev K., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_e8lhsdkuaq34tn285eh6911h8q