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Immune checkpoint molecules are regulated by transforming growth factor (TGF)-β1-induced epithelial-to-mesenchymal transition in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer with a high mortality rate. Epithelial-to-mesenchymal transition (EMT) confers cancer cells with immune evasive ability by modulating the expression of immune checkpoints in many cancers. Thus, the aim of our study is to...

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Detalles Bibliográficos
Autores principales: Shrestha, Ritu, Bridle, Kim R., Crawford, Darrell H. G., Jayachandran, Aparna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8176170/
https://www.ncbi.nlm.nih.gov/pubmed/34104078
http://dx.doi.org/10.7150/ijms.54239