Cargando…

CDK5 Knockdown inhibits proliferation and induces apoptosis and Cell Cycle Arrest in Human Glioblastoma

Aims: Gliomas are the most common malignant brain neoplasms with high recurrence and lethality rates. Recently, studies have reported that cyclin-dependent kinase 5 (CDK5) is involved in tumorigenesis. Herein, we applied bioinformatics analysis to determine the clinical value of CDK5 in patients wit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Yan, Wang, Xuan, Lv, Peng, Yu, Hao, Jiang, Xiaobing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8176241/ https://www.ncbi.nlm.nih.gov/pubmed/34093802 http://dx.doi.org/10.7150/jca.53981

Ejemplares similares

Sulforaphane-cysteine downregulates CDK4 /CDK6 and inhibits tubulin polymerization contributing to cell cycle arrest and apoptosis in human glioblastoma cells
por: Li, Juntao, et al.
Publicado: (2020)

The CDK inhibitor AT7519 inhibits human glioblastoma cell growth by inducing apoptosis, pyroptosis and cell cycle arrest
por: Zhao, Wenpeng, et al.
Publicado: (2023)

REG γ knockdown suppresses proliferation by inducing apoptosis and cell cycle arrest in osteosarcoma
por: Yin, Zhiqiang, et al.
Publicado: (2020)

HOXA10 knockdown inhibits proliferation, induces cell cycle arrest and apoptosis in hepatocellular carcinoma cells through HDAC1
por: Zhang, Yi, et al.
Publicado: (2019)

Knockdown of MRPL42 suppresses glioma cell proliferation by inducing cell cycle arrest and apoptosis
por: Hao, Chunyan, et al.
Publicado: (2018)

Depletion of thymopoietin inhibits proliferation and induces cell cycle arrest/apoptosis in glioblastoma cells
por: Zhang, Lin, et al.
Publicado: (2016)

KIAA0101 knockdown inhibits cell proliferation and induces cell cycle arrest and cell apoptosis in chronic lymphocytic leukemia cells
por: Zhang, Qing, et al.
Publicado: (2021)

Selective CDK7 inhibition with BS-181 suppresses cell proliferation and induces cell cycle arrest and apoptosis in gastric cancer
por: Wang, Bo-Yong, et al.
Publicado: (2016)

Sirtuin 2 knockdown inhibits cell proliferation and RAS/ERK signaling, and promotes cell apoptosis and cell cycle arrest in multiple myeloma
por: Ding, Tianling, et al.
Publicado: (2021)

Knockdown of Expression of Cdk5 or p35 (a Cdk5 Activator) Results in Podocyte Apoptosis
por: Zheng, Ya-Li, et al.
Publicado: (2016)

Mechanisms of Cell Cycle Arrest and Apoptosis in Glioblastoma
por: Gousias, Konstantinos, et al.
Publicado: (2022)

Bombyx mori Dihydroorotate Dehydrogenase: Knockdown Inhibits Cell Growth and Proliferation via Inducing Cell Cycle Arrest
por: Zhao, Erhu, et al.
Publicado: (2018)

A Potential Anti-Glioblastoma Compound LH20 Induces Apoptosis and Arrest of Human Glioblastoma Cells via CDK4/6 Inhibition
por: Wang, Yan, et al.
Publicado: (2023)

Tectorigenin Inhibits Glioblastoma Proliferation by G0/G1 Cell Cycle Arrest
por: Yeh, Liang-Tsai, et al.
Publicado: (2020)

Tizoxanide Promotes Apoptosis in Glioblastoma by Inhibiting CDK1 Activity
por: Huang, Si, et al.
Publicado: (2022)

Glycyrrhizic Acid Inhibits Proliferation of Gastric Cancer Cells by Inducing Cell Cycle Arrest and Apoptosis
por: Wang, Hao, et al.
Publicado: (2020)

YWHAB knockdown inhibits cell proliferation whilst promoting cell cycle arrest and apoptosis in colon cancer cells through PIK3R2
por: Zhou, Xin, et al.
Publicado: (2023)

Haloperidol Induced Cell Cycle Arrest and Apoptosis in Glioblastoma Cells
por: Papadopoulos, Fotios, et al.
Publicado: (2020)

Knockdown of cyclooxygenase-2 leads to growth inhibition and cell cycle arrest in hepatocellular carcinoma cells
por: Lv, Xiuhe, et al.
Publicado: (2019)

Resveratrol inhibits proliferation in human colorectal carcinoma cells by inducing G(1)/S-phase cell cycle arrest and apoptosis through caspase/cyclin-CDK pathways
por: LIU, BIN, et al.
Publicado: (2014)

Osthole inhibits proliferation of human breast cancer cells by inducing cell cycle arrest and apoptosis
por: Wang, Lintao, et al.
Publicado: (2015)

HBXIP knockdown inhibits FHL2 to promote cycle arrest and suppress cervical cancer cell proliferation, invasion and migration
por: Gao, Xia, et al.
Publicado: (2023)

TBX3 knockdown suppresses the proliferation of hypopharyngeal carcinoma FaDu cells by inducing G1/S cell cycle arrest and apoptosis
por: Huang, Yongjiu, et al.
Publicado: (2020)

Overexpression of chromodomain helicase DNA binding protein 5 (CHD5) inhibits cell proliferation and induces cell cycle arrest and apoptosis in chronic myeloid leukemia
por: Xiong, Shilin, et al.
Publicado: (2021)

T. gondii RP Promoters & Knockdown Reveal Molecular Pathways Associated with Proliferation and Cell-Cycle Arrest
por: Hutson, Samuel L., et al.
Publicado: (2010)

Cdk5 phosphorylates non-genotoxically overexpressed p53 following inhibition of PP2A to induce cell cycle arrest/apoptosis and inhibits tumor progression
por: Ajay, Amrendra K, et al.
Publicado: (2010)

Knockdown of immature colon carcinoma transcript-1 inhibits proliferation of glioblastoma multiforme cells through Gap 2/mitotic phase arrest
por: Xie, Rong, et al.
Publicado: (2015)

Knockdown of DLGAP5 suppresses cell proliferation, induces G(2)/M phase arrest and apoptosis in ovarian cancer
por: Zhang, Huijun, et al.
Publicado: (2021)

Knockdown of carboxypeptidase A4 (CPA4) inhibits gastric cancer cell progression via cell cycle arrest and apoptosis
por: Lei, Xinyi, et al.
Publicado: (2022)

Knockdown of SNHG16 suppresses the proliferation and induces the apoptosis of leukemia cells via miR-193a-5p/CDK8
por: Piao, Meihua, et al.
Publicado: (2020)

Chinese Propolis Inhibits the Proliferation of Human Gastric Cancer Cells by Inducing Apoptosis and Cell Cycle Arrest
por: Jiang, Xia-sen, et al.
Publicado: (2020)

JSI-124 Induces Cell Cycle Arrest and Regulates the Apoptosis in Glioblastoma Cells
por: Tsai, Tai-Hsin, et al.
Publicado: (2023)

Knockdown of GGCT inhibits cell proliferation and induces late apoptosis in human gastric cancer
por: Zhang, Wenjie, et al.
Publicado: (2016)

Knockdown of Immature Colon Carcinoma Transcript-1 Inhibits Proliferation of Glioblastoma Multiforme Cells through Gap 2/Mitotic Phase Arrest [Retraction]
Publicado: (2023)

Wogonin inhibits the proliferation of myelodysplastic syndrome cells through the induction of cell cycle arrest and apoptosis
por: LU, HUIXIA, et al.
Publicado: (2015)

Flubendazole inhibits glioma proliferation by G2/M cell cycle arrest and pro-apoptosis
por: Zhou, Xumin, et al.
Publicado: (2018)

Diosmetin Inhibits Cell Proliferation, Induces Cell Apoptosis and Cell Cycle Arrest in Liver Cancer
por: Ma, Aiqing, et al.
Publicado: (2020)

Dimethylfumarate Inhibits Colorectal Carcinoma Cell Proliferation: Evidence for Cell Cycle Arrest, Apoptosis and Autophagy
por: Kaluzki, Irina, et al.
Publicado: (2019)

Knockdown of CLAUDIN-6 Inhibited Apoptosis and Induced Proliferation of Bovine Cumulus Cells
por: Wang, Wanjie, et al.
Publicado: (2022)

Physalis pubescens L. branch and leaf extracts inhibit lymphoma proliferation by inducing apoptosis and cell cycle arrest
por: Yuan-Ce, Li, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_dcu94v24fqpc01qbfdbp1qspk6