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Dapagliflozin Alleviates Hepatic Steatosis by Restoring Autophagy via the AMPK-mTOR Pathway
As a newly approved oral hypoglycaemic agent, the sodium-glucose cotransporter 2 (SGLT2) inhibitor dapagliflozin, which is derived from the natural product phlorizin can effectively reduce blood glucose. Recent clinical studies have found that dapagliflozin alleviates non-alcoholic fatty liver disea...
Autores principales: | Li, Liuran, Li, Qinghua, Huang, Wenbin, Han, Yibing, Tan, Huiting, An, Min, Xiang, Qianru, Zhou, Rui, Yang, Li, Cheng, Yanzhen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8176308/ https://www.ncbi.nlm.nih.gov/pubmed/34093169 http://dx.doi.org/10.3389/fphar.2021.589273 |
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