Luteolin promotes macrophage-mediated phagocytosis by inhibiting CD47 pyroglutamation

‘Don't eat me’ signal of CD47 is activated via its interaction with SIRPα protein on myeloid cells, especially phagocytic cells, and prevents malignant cells from anti-tumor immunity in which pyroglutamate modification of CD47 by glutaminyl-peptide cyclotransferase-like protein (isoQC) takes an...

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Detalles Bibliográficos
Autores principales: Li, Zhiqiang, Gu, Xuemei, Rao, Danni, Lu, Meiling, Wen, Jing, Chen, Xinyan, Wang, Hongbing, Cui, Xianghuan, Tang, Wenwen, Xu, Shilin, Wang, Ping, Yu, Lei, Ge, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8176368/
https://www.ncbi.nlm.nih.gov/pubmed/34051623
http://dx.doi.org/10.1016/j.tranon.2021.101129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8176368/
https://www.ncbi.nlm.nih.gov/pubmed/34051623
http://dx.doi.org/10.1016/j.tranon.2021.101129

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