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Protocol to establish cancer-associated fibroblasts from surgically resected tissues and generate senescent fibroblasts
Accumulating evidence suggests that the malignant behavior of cancer is influenced by stromal activity in the tumor microenvironment. Cancer-associated fibroblasts (CAFs), which are the main component of the cancerous stroma, play an important role in cancer development. Here, we describe a protocol...
Autores principales: | Yasuda, Tadahito, Koiwa, Mayu, Yonemura, Atsuko, Akiyama, Takahiko, Baba, Hideo, Ishimoto, Takatsugu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8176369/ https://www.ncbi.nlm.nih.gov/pubmed/34136831 http://dx.doi.org/10.1016/j.xpro.2021.100553 |
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