Targeting CD276 by CAR-T cells induces regression of esophagus squamous cell carcinoma in xenograft mouse models

Esophageal cancer, including esophageal squamous cell carcinoma (ESCC) and esophageal adenocarcinoma (EAC), has a poor prognosis and limited therapeutic options. Chimeric antigen receptor (CAR)-T cells represent a potential ESCC treatment. In this study, we examined CD276 expression in healthy and e...

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Detalles Bibliográficos
Autores principales: Xuan, Yujing, Sheng, Yuqiao, Zhang, Daiqun, Zhang, Kai, Zhang, Zhen, Ping, Yu, Wang, Shumin, Shi, Xiaojuan, Lian, Jingyao, Liu, Kangdong, Zhang, Yi, Li, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8176370/
https://www.ncbi.nlm.nih.gov/pubmed/34052626
http://dx.doi.org/10.1016/j.tranon.2021.101138

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