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Receptor-interacting protein in malignant digestive neoplasms

A deep and comprehensive understanding of factors that contribute to cancer initiation, progression, and evolution is of essential importance. Among them, the serine/threonine and tyrosine kinase-like kinases, also known as receptor interacting proteins (RIPs) or receptor interacting protein kinases...

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Autores principales: Zhang, Lilong, Guo, Wenyi, Yu, Jia, Li, Chunlei, Li, Man, Chai, Dongqi, Wang, Weixing, Deng, Wenhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8176420/
https://www.ncbi.nlm.nih.gov/pubmed/34093836
http://dx.doi.org/10.7150/jca.57076
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author Zhang, Lilong
Guo, Wenyi
Yu, Jia
Li, Chunlei
Li, Man
Chai, Dongqi
Wang, Weixing
Deng, Wenhong
author_facet Zhang, Lilong
Guo, Wenyi
Yu, Jia
Li, Chunlei
Li, Man
Chai, Dongqi
Wang, Weixing
Deng, Wenhong
author_sort Zhang, Lilong
collection PubMed
description A deep and comprehensive understanding of factors that contribute to cancer initiation, progression, and evolution is of essential importance. Among them, the serine/threonine and tyrosine kinase-like kinases, also known as receptor interacting proteins (RIPs) or receptor interacting protein kinases (RIPKs), is emerging as important tumor-related proteins due to its complex regulation of cell survival, apoptosis, and necrosis. In this review, we mainly review the relevance of RIP to various malignant digestive neoplasms, including esophageal cancer, gastric cancer, colorectal cancer, hepatocellular carcinoma, gallbladder cancer, cholangiocarcinoma, and pancreatic cancer. Consecutive research on RIPs and its relationship with malignant digestive neoplasms is required, as it ultimately conduces to the etiology and treatment of cancer.
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spelling pubmed-81764202021-06-04 Receptor-interacting protein in malignant digestive neoplasms Zhang, Lilong Guo, Wenyi Yu, Jia Li, Chunlei Li, Man Chai, Dongqi Wang, Weixing Deng, Wenhong J Cancer Review A deep and comprehensive understanding of factors that contribute to cancer initiation, progression, and evolution is of essential importance. Among them, the serine/threonine and tyrosine kinase-like kinases, also known as receptor interacting proteins (RIPs) or receptor interacting protein kinases (RIPKs), is emerging as important tumor-related proteins due to its complex regulation of cell survival, apoptosis, and necrosis. In this review, we mainly review the relevance of RIP to various malignant digestive neoplasms, including esophageal cancer, gastric cancer, colorectal cancer, hepatocellular carcinoma, gallbladder cancer, cholangiocarcinoma, and pancreatic cancer. Consecutive research on RIPs and its relationship with malignant digestive neoplasms is required, as it ultimately conduces to the etiology and treatment of cancer. Ivyspring International Publisher 2021-05-19 /pmc/articles/PMC8176420/ /pubmed/34093836 http://dx.doi.org/10.7150/jca.57076 Text en © The author(s) https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). See http://ivyspring.com/terms for full terms and conditions.
spellingShingle Review
Zhang, Lilong
Guo, Wenyi
Yu, Jia
Li, Chunlei
Li, Man
Chai, Dongqi
Wang, Weixing
Deng, Wenhong
Receptor-interacting protein in malignant digestive neoplasms
title Receptor-interacting protein in malignant digestive neoplasms
title_full Receptor-interacting protein in malignant digestive neoplasms
title_fullStr Receptor-interacting protein in malignant digestive neoplasms
title_full_unstemmed Receptor-interacting protein in malignant digestive neoplasms
title_short Receptor-interacting protein in malignant digestive neoplasms
title_sort receptor-interacting protein in malignant digestive neoplasms
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8176420/
https://www.ncbi.nlm.nih.gov/pubmed/34093836
http://dx.doi.org/10.7150/jca.57076
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