Cargando…
Receptor-interacting protein in malignant digestive neoplasms
A deep and comprehensive understanding of factors that contribute to cancer initiation, progression, and evolution is of essential importance. Among them, the serine/threonine and tyrosine kinase-like kinases, also known as receptor interacting proteins (RIPs) or receptor interacting protein kinases...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8176420/ https://www.ncbi.nlm.nih.gov/pubmed/34093836 http://dx.doi.org/10.7150/jca.57076 |
_version_ | 1783703256523866112 |
---|---|
author | Zhang, Lilong Guo, Wenyi Yu, Jia Li, Chunlei Li, Man Chai, Dongqi Wang, Weixing Deng, Wenhong |
author_facet | Zhang, Lilong Guo, Wenyi Yu, Jia Li, Chunlei Li, Man Chai, Dongqi Wang, Weixing Deng, Wenhong |
author_sort | Zhang, Lilong |
collection | PubMed |
description | A deep and comprehensive understanding of factors that contribute to cancer initiation, progression, and evolution is of essential importance. Among them, the serine/threonine and tyrosine kinase-like kinases, also known as receptor interacting proteins (RIPs) or receptor interacting protein kinases (RIPKs), is emerging as important tumor-related proteins due to its complex regulation of cell survival, apoptosis, and necrosis. In this review, we mainly review the relevance of RIP to various malignant digestive neoplasms, including esophageal cancer, gastric cancer, colorectal cancer, hepatocellular carcinoma, gallbladder cancer, cholangiocarcinoma, and pancreatic cancer. Consecutive research on RIPs and its relationship with malignant digestive neoplasms is required, as it ultimately conduces to the etiology and treatment of cancer. |
format | Online Article Text |
id | pubmed-8176420 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Ivyspring International Publisher |
record_format | MEDLINE/PubMed |
spelling | pubmed-81764202021-06-04 Receptor-interacting protein in malignant digestive neoplasms Zhang, Lilong Guo, Wenyi Yu, Jia Li, Chunlei Li, Man Chai, Dongqi Wang, Weixing Deng, Wenhong J Cancer Review A deep and comprehensive understanding of factors that contribute to cancer initiation, progression, and evolution is of essential importance. Among them, the serine/threonine and tyrosine kinase-like kinases, also known as receptor interacting proteins (RIPs) or receptor interacting protein kinases (RIPKs), is emerging as important tumor-related proteins due to its complex regulation of cell survival, apoptosis, and necrosis. In this review, we mainly review the relevance of RIP to various malignant digestive neoplasms, including esophageal cancer, gastric cancer, colorectal cancer, hepatocellular carcinoma, gallbladder cancer, cholangiocarcinoma, and pancreatic cancer. Consecutive research on RIPs and its relationship with malignant digestive neoplasms is required, as it ultimately conduces to the etiology and treatment of cancer. Ivyspring International Publisher 2021-05-19 /pmc/articles/PMC8176420/ /pubmed/34093836 http://dx.doi.org/10.7150/jca.57076 Text en © The author(s) https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). See http://ivyspring.com/terms for full terms and conditions. |
spellingShingle | Review Zhang, Lilong Guo, Wenyi Yu, Jia Li, Chunlei Li, Man Chai, Dongqi Wang, Weixing Deng, Wenhong Receptor-interacting protein in malignant digestive neoplasms |
title | Receptor-interacting protein in malignant digestive neoplasms |
title_full | Receptor-interacting protein in malignant digestive neoplasms |
title_fullStr | Receptor-interacting protein in malignant digestive neoplasms |
title_full_unstemmed | Receptor-interacting protein in malignant digestive neoplasms |
title_short | Receptor-interacting protein in malignant digestive neoplasms |
title_sort | receptor-interacting protein in malignant digestive neoplasms |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8176420/ https://www.ncbi.nlm.nih.gov/pubmed/34093836 http://dx.doi.org/10.7150/jca.57076 |
work_keys_str_mv | AT zhanglilong receptorinteractingproteininmalignantdigestiveneoplasms AT guowenyi receptorinteractingproteininmalignantdigestiveneoplasms AT yujia receptorinteractingproteininmalignantdigestiveneoplasms AT lichunlei receptorinteractingproteininmalignantdigestiveneoplasms AT liman receptorinteractingproteininmalignantdigestiveneoplasms AT chaidongqi receptorinteractingproteininmalignantdigestiveneoplasms AT wangweixing receptorinteractingproteininmalignantdigestiveneoplasms AT dengwenhong receptorinteractingproteininmalignantdigestiveneoplasms |