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MicroRNA-1246 by Targeting AXIN2 and GSK-3β Overcomes Drug Resistance and Induces Apoptosis in Chemo-resistant Leukemia Cells

Background and objective: Chemotherapy plays an important role in the treatment of leukemia. Multidrug resistance (MDR) induced by chemotherapy always leads to treatment failure and disease recurrence. MicroRNAs (miRNAs) have been verified as crucial components in carcinogenesis, including chemo-res...

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Detalles Bibliográficos
Autores principales: Xie, Bei, Li, Linjing, Zhang, Zhewen, Zhao, Lei, Cheng, Juan, Zhou, Cunmin, Cheng, Jie, Yan, Jing, Chen, Jing, Yi, Juan, Wang, Bei, Jin, Suya, Wei, Hulai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8176421/
https://www.ncbi.nlm.nih.gov/pubmed/34093820
http://dx.doi.org/10.7150/jca.58522