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Generating Informative Sequence Tags from Antigen-Binding Regions of Heavily Glycosylated IgA1 Antibodies by Native Top-Down Electron Capture Dissociation

[Image: see text] Immunoglobulins A (IgA) include some of the most abundant human antibodies and play an important role in defending mucosal surfaces against pathogens. The unique structural features of the heavy chain of IgA subclasses (called IgA1 and IgA2) enable them to polymerize via the joinin...

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Detalles Bibliográficos
Autores principales:	Greisch, Jean-Francois, den Boer, Maurits A., Beurskens, Frank, Schuurman, Janine, Tamara, Sem, Bondt, Albert, Heck, Albert J. R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8176452/ https://www.ncbi.nlm.nih.gov/pubmed/33570406 http://dx.doi.org/10.1021/jasms.0c00461

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