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Dengue Virus Infections among Peace Corps Volunteers in Timor-Leste, 2018–2019

Dengue is an ongoing health risk for Peace Corps Volunteers (PCVs) working in the tropics. On May 2019, the Peace Corps Office of Health Services notified the Centers for Disease Control and Prevention (CDC) of a dengue outbreak among PCVs in Timor-Leste. The purpose of this investigation was to ide...

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Autores principales: Sánchez-González, Liliana, Venuto, Margaret, Poe, Scott, Major, Chelsea G., Baskara, Leonardus, Abdiyeva, Sevinj, Murphy, Daniel, Munoz-Jordan, Jorge L., Medina, Freddy A., Paz-Bailey, Gabriela, Petersen, Kyle, Becker, Karen, Sharp, Tyler M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Tropical Medicine and Hygiene 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8176509/
https://www.ncbi.nlm.nih.gov/pubmed/33901000
http://dx.doi.org/10.4269/ajtmh.21-0020
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author Sánchez-González, Liliana
Venuto, Margaret
Poe, Scott
Major, Chelsea G.
Baskara, Leonardus
Abdiyeva, Sevinj
Murphy, Daniel
Munoz-Jordan, Jorge L.
Medina, Freddy A.
Paz-Bailey, Gabriela
Petersen, Kyle
Becker, Karen
Sharp, Tyler M.
author_facet Sánchez-González, Liliana
Venuto, Margaret
Poe, Scott
Major, Chelsea G.
Baskara, Leonardus
Abdiyeva, Sevinj
Murphy, Daniel
Munoz-Jordan, Jorge L.
Medina, Freddy A.
Paz-Bailey, Gabriela
Petersen, Kyle
Becker, Karen
Sharp, Tyler M.
author_sort Sánchez-González, Liliana
collection PubMed
description Dengue is an ongoing health risk for Peace Corps Volunteers (PCVs) working in the tropics. On May 2019, the Peace Corps Office of Health Services notified the Centers for Disease Control and Prevention (CDC) of a dengue outbreak among PCVs in Timor-Leste. The purpose of this investigation was to identify the clinical, demographic, and epidemiological characteristics of PCVs with dengue and recommend dengue preventive measures. To identify PCVs with dengue and describe disease severity, the medical records of PCVs reporting fever during September 2018–June 2019 were reviewed. To identify factors associated with dengue virus (DENV) infection, we administered a questionnaire on demographics, travel history, and mosquito avoidance behaviors and collected blood specimens to detect the anti-DENV IgM antibody to diagnose recent infection. Of 35 PCVs in-country, 11 (31%) tested positive for dengue (NS1, IgM, PCR), eight requiring hospitalization and medical evacuation. Among 27 (77%) PCVs who participated in the investigation, all reported having been recently bitten by mosquitoes and 56% reported being bitten most often at home; only 16 (59%) reported having screens on bedroom windows. Nearly all (93%) PCVs reported using a bed net every night; fewer (70%) reported using mosquito repellent at least once a day. No behaviors were significantly associated with DENV infection. Raising awareness of dengue risk among PCVs and continuing to encourage mosquito avoidance behavior to prevent dengue is critical. Access to and use of measures to avoid mosquito bites should be improved or implemented. Peace Corps medical officers should continue to receive an annual refresher training on dengue clinical management.
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spelling pubmed-81765092021-06-07 Dengue Virus Infections among Peace Corps Volunteers in Timor-Leste, 2018–2019 Sánchez-González, Liliana Venuto, Margaret Poe, Scott Major, Chelsea G. Baskara, Leonardus Abdiyeva, Sevinj Murphy, Daniel Munoz-Jordan, Jorge L. Medina, Freddy A. Paz-Bailey, Gabriela Petersen, Kyle Becker, Karen Sharp, Tyler M. Am J Trop Med Hyg Articles Dengue is an ongoing health risk for Peace Corps Volunteers (PCVs) working in the tropics. On May 2019, the Peace Corps Office of Health Services notified the Centers for Disease Control and Prevention (CDC) of a dengue outbreak among PCVs in Timor-Leste. The purpose of this investigation was to identify the clinical, demographic, and epidemiological characteristics of PCVs with dengue and recommend dengue preventive measures. To identify PCVs with dengue and describe disease severity, the medical records of PCVs reporting fever during September 2018–June 2019 were reviewed. To identify factors associated with dengue virus (DENV) infection, we administered a questionnaire on demographics, travel history, and mosquito avoidance behaviors and collected blood specimens to detect the anti-DENV IgM antibody to diagnose recent infection. Of 35 PCVs in-country, 11 (31%) tested positive for dengue (NS1, IgM, PCR), eight requiring hospitalization and medical evacuation. Among 27 (77%) PCVs who participated in the investigation, all reported having been recently bitten by mosquitoes and 56% reported being bitten most often at home; only 16 (59%) reported having screens on bedroom windows. Nearly all (93%) PCVs reported using a bed net every night; fewer (70%) reported using mosquito repellent at least once a day. No behaviors were significantly associated with DENV infection. Raising awareness of dengue risk among PCVs and continuing to encourage mosquito avoidance behavior to prevent dengue is critical. Access to and use of measures to avoid mosquito bites should be improved or implemented. Peace Corps medical officers should continue to receive an annual refresher training on dengue clinical management. The American Society of Tropical Medicine and Hygiene 2021-06 2021-04-26 /pmc/articles/PMC8176509/ /pubmed/33901000 http://dx.doi.org/10.4269/ajtmh.21-0020 Text en © The American Society of Tropical Medicine and Hygiene https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution (CC-BY) License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Articles
Sánchez-González, Liliana
Venuto, Margaret
Poe, Scott
Major, Chelsea G.
Baskara, Leonardus
Abdiyeva, Sevinj
Murphy, Daniel
Munoz-Jordan, Jorge L.
Medina, Freddy A.
Paz-Bailey, Gabriela
Petersen, Kyle
Becker, Karen
Sharp, Tyler M.
Dengue Virus Infections among Peace Corps Volunteers in Timor-Leste, 2018–2019
title Dengue Virus Infections among Peace Corps Volunteers in Timor-Leste, 2018–2019
title_full Dengue Virus Infections among Peace Corps Volunteers in Timor-Leste, 2018–2019
title_fullStr Dengue Virus Infections among Peace Corps Volunteers in Timor-Leste, 2018–2019
title_full_unstemmed Dengue Virus Infections among Peace Corps Volunteers in Timor-Leste, 2018–2019
title_short Dengue Virus Infections among Peace Corps Volunteers in Timor-Leste, 2018–2019
title_sort dengue virus infections among peace corps volunteers in timor-leste, 2018–2019
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8176509/
https://www.ncbi.nlm.nih.gov/pubmed/33901000
http://dx.doi.org/10.4269/ajtmh.21-0020
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