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YTHDF1 promotes hepatocellular carcinoma progression via activating PI3K/AKT/mTOR signaling pathway and inducing epithelial-mesenchymal transition
BACKGROUND: N(6)-methyladenosine (m(6)A) modification, as the most abundant RNA modification, widely participates in the physiological process and is involved in multiple disease progression, especially cancer. YTH N6-methyladenosine RNA binding protein 1 (YTHDF1) is a pivotal m(6)A “reader” protein...
Autores principales: | Luo, Xiangyuan, Cao, Mengdie, Gao, Fan, He, Xingxing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8176587/ https://www.ncbi.nlm.nih.gov/pubmed/34088349 http://dx.doi.org/10.1186/s40164-021-00227-0 |
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