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Does Universal Screening for Gestational Diabetes Mellitus Improve Neonatal Outcomes in a Socially Vulnerable Population: A Prospective Study in French Guiana

AIMS/INTRODUCTION: French Guiana has a high prevalence of metabolic diseases, which are risk factors for gestational diabetes mellitus. Despite routine screening for gestational diabetes, treatment is still challenging because of health inequalities and different cultural representations of disease...

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Autores principales: Leonco, Loic, Kallel, Hatem, Nacher, Mathieu, Thelusme, Liliane, Dueymes, Maryvonne, Mhiri, Raoudha, Lalanne-Mistrih, Marie Laure, Sabbah, Nadia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8176854/
https://www.ncbi.nlm.nih.gov/pubmed/34093431
http://dx.doi.org/10.3389/fendo.2021.644770
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author Leonco, Loic
Kallel, Hatem
Nacher, Mathieu
Thelusme, Liliane
Dueymes, Maryvonne
Mhiri, Raoudha
Lalanne-Mistrih, Marie Laure
Sabbah, Nadia
author_facet Leonco, Loic
Kallel, Hatem
Nacher, Mathieu
Thelusme, Liliane
Dueymes, Maryvonne
Mhiri, Raoudha
Lalanne-Mistrih, Marie Laure
Sabbah, Nadia
author_sort Leonco, Loic
collection PubMed
description AIMS/INTRODUCTION: French Guiana has a high prevalence of metabolic diseases, which are risk factors for gestational diabetes mellitus. Despite routine screening for gestational diabetes, treatment is still challenging because of health inequalities and different cultural representations of disease and pregnancy. This study was conducted to assess the role of early and universal GDM screening on obstetrical and neonatal complications in a socially deprived population. MATERIALS AND METHODS: A prospective study was conducted, in the level III maternity in French Guiana. Of 2136 deliveries, 223 had gestational diabetes mellitus, 110 of whom were followed-up for 6 month to detail their social and laboratory parameters. RESULTS: The prevalence of gestational diabetes in French Guiana (Cayenne Hospital) was estimated at 10.3%. The study population was very precarious with 70% of patients on welfare (universal health coverage or state medical assistance). The following obstetrical complications were observed: cesarean delivery (32%), history of miscarriage (26%) and preeclampsia (7.4%). Nevertheless, neonatal complications were rarely present and included hypoglycemia (2.8%) and macrosomia (2.8%). CONCLUSION: In French Guiana, gestational diabetes mellitus is very common. However, in a context of widespread poverty and diverse cultural representations, universal screening and monitoring limited the risk of macrosomia.
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spelling pubmed-81768542021-06-05 Does Universal Screening for Gestational Diabetes Mellitus Improve Neonatal Outcomes in a Socially Vulnerable Population: A Prospective Study in French Guiana Leonco, Loic Kallel, Hatem Nacher, Mathieu Thelusme, Liliane Dueymes, Maryvonne Mhiri, Raoudha Lalanne-Mistrih, Marie Laure Sabbah, Nadia Front Endocrinol (Lausanne) Endocrinology AIMS/INTRODUCTION: French Guiana has a high prevalence of metabolic diseases, which are risk factors for gestational diabetes mellitus. Despite routine screening for gestational diabetes, treatment is still challenging because of health inequalities and different cultural representations of disease and pregnancy. This study was conducted to assess the role of early and universal GDM screening on obstetrical and neonatal complications in a socially deprived population. MATERIALS AND METHODS: A prospective study was conducted, in the level III maternity in French Guiana. Of 2136 deliveries, 223 had gestational diabetes mellitus, 110 of whom were followed-up for 6 month to detail their social and laboratory parameters. RESULTS: The prevalence of gestational diabetes in French Guiana (Cayenne Hospital) was estimated at 10.3%. The study population was very precarious with 70% of patients on welfare (universal health coverage or state medical assistance). The following obstetrical complications were observed: cesarean delivery (32%), history of miscarriage (26%) and preeclampsia (7.4%). Nevertheless, neonatal complications were rarely present and included hypoglycemia (2.8%) and macrosomia (2.8%). CONCLUSION: In French Guiana, gestational diabetes mellitus is very common. However, in a context of widespread poverty and diverse cultural representations, universal screening and monitoring limited the risk of macrosomia. Frontiers Media S.A. 2021-05-21 /pmc/articles/PMC8176854/ /pubmed/34093431 http://dx.doi.org/10.3389/fendo.2021.644770 Text en Copyright © 2021 Leonco, Kallel, Nacher, Thelusme, Dueymes, Mhiri, Lalanne-Mistrih and Sabbah https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Endocrinology
Leonco, Loic
Kallel, Hatem
Nacher, Mathieu
Thelusme, Liliane
Dueymes, Maryvonne
Mhiri, Raoudha
Lalanne-Mistrih, Marie Laure
Sabbah, Nadia
Does Universal Screening for Gestational Diabetes Mellitus Improve Neonatal Outcomes in a Socially Vulnerable Population: A Prospective Study in French Guiana
title Does Universal Screening for Gestational Diabetes Mellitus Improve Neonatal Outcomes in a Socially Vulnerable Population: A Prospective Study in French Guiana
title_full Does Universal Screening for Gestational Diabetes Mellitus Improve Neonatal Outcomes in a Socially Vulnerable Population: A Prospective Study in French Guiana
title_fullStr Does Universal Screening for Gestational Diabetes Mellitus Improve Neonatal Outcomes in a Socially Vulnerable Population: A Prospective Study in French Guiana
title_full_unstemmed Does Universal Screening for Gestational Diabetes Mellitus Improve Neonatal Outcomes in a Socially Vulnerable Population: A Prospective Study in French Guiana
title_short Does Universal Screening for Gestational Diabetes Mellitus Improve Neonatal Outcomes in a Socially Vulnerable Population: A Prospective Study in French Guiana
title_sort does universal screening for gestational diabetes mellitus improve neonatal outcomes in a socially vulnerable population: a prospective study in french guiana
topic Endocrinology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8176854/
https://www.ncbi.nlm.nih.gov/pubmed/34093431
http://dx.doi.org/10.3389/fendo.2021.644770
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