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The Global, Regional, and National Burden and Trends of Breast Cancer From 1990 to 2019: Results From the Global Burden of Disease Study 2019
BACKGROUND: The burden of breast cancer has been increasing globally. The epidemiology burden and trends need to be updated. This study aimed to update the burden and trends of breast cancer incidences, deaths, and disability-adjusted life-years (DALYs) from 1990 to 2019, using the Global Burden of...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8176863/ https://www.ncbi.nlm.nih.gov/pubmed/34094989 http://dx.doi.org/10.3389/fonc.2021.689562 |
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author | Xu, Shangbo Liu, Yiyuan Zhang, Taofeng Zheng, Jiehua Lin, Weixun Cai, Jiehui Zou, Juan Chen, Yaokun Xie, Yanna Chen, Yexi Li, Zhiyang |
author_facet | Xu, Shangbo Liu, Yiyuan Zhang, Taofeng Zheng, Jiehua Lin, Weixun Cai, Jiehui Zou, Juan Chen, Yaokun Xie, Yanna Chen, Yexi Li, Zhiyang |
author_sort | Xu, Shangbo |
collection | PubMed |
description | BACKGROUND: The burden of breast cancer has been increasing globally. The epidemiology burden and trends need to be updated. This study aimed to update the burden and trends of breast cancer incidences, deaths, and disability-adjusted life-years (DALYs) from 1990 to 2019, using the Global Burden of Disease 2019 study. METHODS: The data of incidences, deaths, DALYs, and age-standardized rates were extracted. Estimated annual percentage changes were used to quantify the trends of age-standardized rates. Besides, the population attributable fractions of the risk factors of breast cancer were also estimated. RESULTS: Globally, the incidences of breast cancer increased to 2,002,354 in 2019. High social-development index (SDI) quintiles had the highest incidence cases with a declining trend in age-standardized incidence rate. In 2019, the global deaths and DALYs of breast cancer increased to 700,660 and 20,625,313, respectively. From 1990 to 2019, the age-standardized mortality rates and age-standardized DALY rates declined globally, especially in high and high-middle SDI quintiles. Besides, the trends varied from different regions and countries. The proportion of the patients in the 70+ years age group increased globally. Deaths of breast cancer attributable to high fasting plasma glucose and high body mass index increased globally, and high fasting plasma glucose was the greatest contributor to the global breast cancer deaths. CONCLUSION: The burden of breast cancer in higher SDI quintiles had gone down while the burden was still on the rise in lower SDI quintiles. It is necessary to appeal to the public to decrease the exposure of the risk factors. |
format | Online Article Text |
id | pubmed-8176863 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-81768632021-06-05 The Global, Regional, and National Burden and Trends of Breast Cancer From 1990 to 2019: Results From the Global Burden of Disease Study 2019 Xu, Shangbo Liu, Yiyuan Zhang, Taofeng Zheng, Jiehua Lin, Weixun Cai, Jiehui Zou, Juan Chen, Yaokun Xie, Yanna Chen, Yexi Li, Zhiyang Front Oncol Oncology BACKGROUND: The burden of breast cancer has been increasing globally. The epidemiology burden and trends need to be updated. This study aimed to update the burden and trends of breast cancer incidences, deaths, and disability-adjusted life-years (DALYs) from 1990 to 2019, using the Global Burden of Disease 2019 study. METHODS: The data of incidences, deaths, DALYs, and age-standardized rates were extracted. Estimated annual percentage changes were used to quantify the trends of age-standardized rates. Besides, the population attributable fractions of the risk factors of breast cancer were also estimated. RESULTS: Globally, the incidences of breast cancer increased to 2,002,354 in 2019. High social-development index (SDI) quintiles had the highest incidence cases with a declining trend in age-standardized incidence rate. In 2019, the global deaths and DALYs of breast cancer increased to 700,660 and 20,625,313, respectively. From 1990 to 2019, the age-standardized mortality rates and age-standardized DALY rates declined globally, especially in high and high-middle SDI quintiles. Besides, the trends varied from different regions and countries. The proportion of the patients in the 70+ years age group increased globally. Deaths of breast cancer attributable to high fasting plasma glucose and high body mass index increased globally, and high fasting plasma glucose was the greatest contributor to the global breast cancer deaths. CONCLUSION: The burden of breast cancer in higher SDI quintiles had gone down while the burden was still on the rise in lower SDI quintiles. It is necessary to appeal to the public to decrease the exposure of the risk factors. Frontiers Media S.A. 2021-05-21 /pmc/articles/PMC8176863/ /pubmed/34094989 http://dx.doi.org/10.3389/fonc.2021.689562 Text en Copyright © 2021 Xu, Liu, Zhang, Zheng, Lin, Cai, Zou, Chen, Xie, Chen and Li https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Oncology Xu, Shangbo Liu, Yiyuan Zhang, Taofeng Zheng, Jiehua Lin, Weixun Cai, Jiehui Zou, Juan Chen, Yaokun Xie, Yanna Chen, Yexi Li, Zhiyang The Global, Regional, and National Burden and Trends of Breast Cancer From 1990 to 2019: Results From the Global Burden of Disease Study 2019 |
title | The Global, Regional, and National Burden and Trends of Breast Cancer From 1990 to 2019: Results From the Global Burden of Disease Study 2019 |
title_full | The Global, Regional, and National Burden and Trends of Breast Cancer From 1990 to 2019: Results From the Global Burden of Disease Study 2019 |
title_fullStr | The Global, Regional, and National Burden and Trends of Breast Cancer From 1990 to 2019: Results From the Global Burden of Disease Study 2019 |
title_full_unstemmed | The Global, Regional, and National Burden and Trends of Breast Cancer From 1990 to 2019: Results From the Global Burden of Disease Study 2019 |
title_short | The Global, Regional, and National Burden and Trends of Breast Cancer From 1990 to 2019: Results From the Global Burden of Disease Study 2019 |
title_sort | global, regional, and national burden and trends of breast cancer from 1990 to 2019: results from the global burden of disease study 2019 |
topic | Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8176863/ https://www.ncbi.nlm.nih.gov/pubmed/34094989 http://dx.doi.org/10.3389/fonc.2021.689562 |
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