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The ALK inhibitors, alectinib and ceritinib, induce ALK‐independent and STAT3‐dependent glioblastoma cell death

Glioblastoma (GBM) is the most common, but extremely malignant, brain tumor; thus, the development of novel therapeutic strategies for GBMs is imperative. Many tyrosine kinase inhibitors (TKIs) have been approved for various cancers, yet none has demonstrated clinical benefit against GBM. Anaplastic...

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Detalles Bibliográficos
Autores principales: Kawauchi, Daisuke, Takahashi, Masamichi, Satomi, Kaishi, Yamamuro, Shun, Kobayashi, Tatsuya, Uchida, Eita, Honda‐Kitahara, Mai, Narita, Yoshitaka, Iwadate, Yasuo, Ichimura, Koichi, Tomiyama, Arata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8177803/
https://www.ncbi.nlm.nih.gov/pubmed/33728771
http://dx.doi.org/10.1111/cas.14885