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Intrinsic attention to pain is associated with a pronociceptive phenotype

INTRODUCTION: Evidence suggests that attention to pain is a product of both incoming sensory signals and cognitive evaluation of a stimulus. Intrinsic attention to pain (IAP) is a measure that captures an individual's natural tendency to attend to a painful stimulus and may be important in unde...

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Autores principales: Adams, Greig, Harrison, Richard, Gandhi, Wiebke, van Reekum, Carien M., Salomons, Tim V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8177874/
https://www.ncbi.nlm.nih.gov/pubmed/34104840
http://dx.doi.org/10.1097/PR9.0000000000000934
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author Adams, Greig
Harrison, Richard
Gandhi, Wiebke
van Reekum, Carien M.
Salomons, Tim V.
author_facet Adams, Greig
Harrison, Richard
Gandhi, Wiebke
van Reekum, Carien M.
Salomons, Tim V.
author_sort Adams, Greig
collection PubMed
description INTRODUCTION: Evidence suggests that attention to pain is a product of both incoming sensory signals and cognitive evaluation of a stimulus. Intrinsic attention to pain (IAP) is a measure that captures an individual's natural tendency to attend to a painful stimulus and may be important in understanding why pain disrupts cognitive functioning in some individuals more than others. OBJECTIVE: In this study, we explored the extent to which IAP was associated with the modulation of incoming sensory signals characteristic of a pronociceptive phenotype: temporal summation (TS) and conditioned pain modulation (CPM). METHOD: 44 healthy participants (23 female; M(age)=23.57, S.D.=5.50) were assessed on IAP, TS and CPM. RESULTS: We found that IAP was positively correlated with TS and CPM. A regression model showed that TS and CPM explained 39% of the variance in IAP scores. Both mechanisms seem to contribute independently to the propensity to attend to pain. CONCLUSION: These findings highlight that modulatory mechanisms at the spinal/supraspinal level exert a strong influence on an individual's ability to disengage from pain.
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spelling pubmed-81778742021-06-07 Intrinsic attention to pain is associated with a pronociceptive phenotype Adams, Greig Harrison, Richard Gandhi, Wiebke van Reekum, Carien M. Salomons, Tim V. Pain Rep Psychology INTRODUCTION: Evidence suggests that attention to pain is a product of both incoming sensory signals and cognitive evaluation of a stimulus. Intrinsic attention to pain (IAP) is a measure that captures an individual's natural tendency to attend to a painful stimulus and may be important in understanding why pain disrupts cognitive functioning in some individuals more than others. OBJECTIVE: In this study, we explored the extent to which IAP was associated with the modulation of incoming sensory signals characteristic of a pronociceptive phenotype: temporal summation (TS) and conditioned pain modulation (CPM). METHOD: 44 healthy participants (23 female; M(age)=23.57, S.D.=5.50) were assessed on IAP, TS and CPM. RESULTS: We found that IAP was positively correlated with TS and CPM. A regression model showed that TS and CPM explained 39% of the variance in IAP scores. Both mechanisms seem to contribute independently to the propensity to attend to pain. CONCLUSION: These findings highlight that modulatory mechanisms at the spinal/supraspinal level exert a strong influence on an individual's ability to disengage from pain. Wolters Kluwer 2021-06-03 /pmc/articles/PMC8177874/ /pubmed/34104840 http://dx.doi.org/10.1097/PR9.0000000000000934 Text en Copyright © 2021 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The International Association for the Study of Pain. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Psychology
Adams, Greig
Harrison, Richard
Gandhi, Wiebke
van Reekum, Carien M.
Salomons, Tim V.
Intrinsic attention to pain is associated with a pronociceptive phenotype
title Intrinsic attention to pain is associated with a pronociceptive phenotype
title_full Intrinsic attention to pain is associated with a pronociceptive phenotype
title_fullStr Intrinsic attention to pain is associated with a pronociceptive phenotype
title_full_unstemmed Intrinsic attention to pain is associated with a pronociceptive phenotype
title_short Intrinsic attention to pain is associated with a pronociceptive phenotype
title_sort intrinsic attention to pain is associated with a pronociceptive phenotype
topic Psychology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8177874/
https://www.ncbi.nlm.nih.gov/pubmed/34104840
http://dx.doi.org/10.1097/PR9.0000000000000934
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