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The critical role of Hedgehog-responsive mesenchymal progenitors in meniscus development and injury repair
Meniscal tears are associated with a high risk of osteoarthritis but currently have no disease-modifying therapies. Using a Gli1 reporter line, we found that Gli1(+) cells contribute to the development of meniscus horns from 2 weeks of age. In adult mice, Gli1(+) cells resided at the superficial lay...
| Autores principales: | , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8177886/ https://www.ncbi.nlm.nih.gov/pubmed/34085927 http://dx.doi.org/10.7554/eLife.62917 |