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Balancing risk in a patient with primary bone histiocytic sarcoma during pregnancy: Case report and review of the literature
INTRODUCTION AND IMPORTANCE: Histiocytic sarcoma (HS) is a rare, aggressive malignant neoplasm of hematopoietic cell origin. Primary HS of the proximal humerus, without involvement of lymph nodes or bone marrow, or systemic features, is very rare. CASE PRESENTATION: We report a rare case of primary...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178090/ https://www.ncbi.nlm.nih.gov/pubmed/34062362 http://dx.doi.org/10.1016/j.ijscr.2021.106021 |
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author | Al-Amri, Ayman Al-Khabori, Murtadha Al-Riyami, Nihal Al-Haddabi, Ibrahim |
author_facet | Al-Amri, Ayman Al-Khabori, Murtadha Al-Riyami, Nihal Al-Haddabi, Ibrahim |
author_sort | Al-Amri, Ayman |
collection | PubMed |
description | INTRODUCTION AND IMPORTANCE: Histiocytic sarcoma (HS) is a rare, aggressive malignant neoplasm of hematopoietic cell origin. Primary HS of the proximal humerus, without involvement of lymph nodes or bone marrow, or systemic features, is very rare. CASE PRESENTATION: We report a rare case of primary bony HS of the proximal humerus without bone marrow involvement in a healthy 33-year-old pregnant woman. She was successfully treated with surgical resection during pregnancy and radiotherapy post-delivery. CLINICAL DISCUSSION: This is the first report of a patient with primary bony HS during pregnancy. This highlights the fact that although HS is a neoplasm of hemolymphoid cell lineage, it frequently arises in non-lymphoid organs. CONCLUSION: This case emphasizes the importance of a multidisciplinary approach and the need for balancing treatment risk in a patient with primary bone HS during pregnancy. |
format | Online Article Text |
id | pubmed-8178090 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-81780902021-06-15 Balancing risk in a patient with primary bone histiocytic sarcoma during pregnancy: Case report and review of the literature Al-Amri, Ayman Al-Khabori, Murtadha Al-Riyami, Nihal Al-Haddabi, Ibrahim Int J Surg Case Rep Case Report INTRODUCTION AND IMPORTANCE: Histiocytic sarcoma (HS) is a rare, aggressive malignant neoplasm of hematopoietic cell origin. Primary HS of the proximal humerus, without involvement of lymph nodes or bone marrow, or systemic features, is very rare. CASE PRESENTATION: We report a rare case of primary bony HS of the proximal humerus without bone marrow involvement in a healthy 33-year-old pregnant woman. She was successfully treated with surgical resection during pregnancy and radiotherapy post-delivery. CLINICAL DISCUSSION: This is the first report of a patient with primary bony HS during pregnancy. This highlights the fact that although HS is a neoplasm of hemolymphoid cell lineage, it frequently arises in non-lymphoid organs. CONCLUSION: This case emphasizes the importance of a multidisciplinary approach and the need for balancing treatment risk in a patient with primary bone HS during pregnancy. Elsevier 2021-05-26 /pmc/articles/PMC8178090/ /pubmed/34062362 http://dx.doi.org/10.1016/j.ijscr.2021.106021 Text en © 2021 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Al-Amri, Ayman Al-Khabori, Murtadha Al-Riyami, Nihal Al-Haddabi, Ibrahim Balancing risk in a patient with primary bone histiocytic sarcoma during pregnancy: Case report and review of the literature |
title | Balancing risk in a patient with primary bone histiocytic sarcoma during pregnancy: Case report and review of the literature |
title_full | Balancing risk in a patient with primary bone histiocytic sarcoma during pregnancy: Case report and review of the literature |
title_fullStr | Balancing risk in a patient with primary bone histiocytic sarcoma during pregnancy: Case report and review of the literature |
title_full_unstemmed | Balancing risk in a patient with primary bone histiocytic sarcoma during pregnancy: Case report and review of the literature |
title_short | Balancing risk in a patient with primary bone histiocytic sarcoma during pregnancy: Case report and review of the literature |
title_sort | balancing risk in a patient with primary bone histiocytic sarcoma during pregnancy: case report and review of the literature |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178090/ https://www.ncbi.nlm.nih.gov/pubmed/34062362 http://dx.doi.org/10.1016/j.ijscr.2021.106021 |
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