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AAV-mediated expression of NFAT decoy oligonucleotides protects from cardiac hypertrophy and heart failure
Previous studies have underlined the substantial role of nuclear factor of activated T cells (NFAT) in hypertension-induced myocardial hypertrophy ultimately leading to heart failure. Here, we aimed at neutralizing four members of the NFAT family of transcription factors as a therapeutic strategy fo...
Autores principales: | Remes, Anca, Wagner, Andreas H., Schmiedel, Nesrin, Heckmann, Markus, Ruf, Theresa, Ding, Lin, Jungmann, Andreas, Senger, Frauke, Katus, Hugo A., Ullrich, Nina D., Frey, Norbert, Hecker, Markus, Müller, Oliver J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178147/ https://www.ncbi.nlm.nih.gov/pubmed/34089101 http://dx.doi.org/10.1007/s00395-021-00880-w |
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