CIP2A regulates MYC translation (via its 5′UTR) in colorectal cancer

BACKGROUND: Deregulated expression of MYC is a driver of colorectal carcinogenesis, suggesting that decreasing MYC expression may have significant therapeutic value. CIP2A is an oncogenic factor that regulates MYC expression. CIP2A is overexpressed in colorectal cancer (CRC), and its expression leve...

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Detalles Bibliográficos
Autores principales: Denk, S., Schmidt, S., Schurr, Y., Schwarz, G., Schote, F., Diefenbacher, M., Armendariz, C., Dejure, F., Eilers, M., Wiegering, Armin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178152/
https://www.ncbi.nlm.nih.gov/pubmed/33078202
http://dx.doi.org/10.1007/s00384-020-03772-y

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