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Celastrol inhibit the proliferation, invasion and migration of human cervical HeLa cancer cells through down‐regulation of MMP‐2 and MMP‐9

The present study evaluated the anticancer potential of celastrol through down‐regulation of matrix metalloproteinase‐2 (MMP‐2) and MMP‐9. HeLa cells were incubated with different concentrations of celastrol (1, 10 and 100 µM) for 48h. Doxorubicin was used as a reference drug. Cancer cell migration,...

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Detalles Bibliográficos
Autores principales: Zhang, Jing, Wang, Ranran, Cheng, Li, Xu, Haisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178258/
https://www.ncbi.nlm.nih.gov/pubmed/33945201
http://dx.doi.org/10.1111/jcmm.16488

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