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Targeted dual inhibition of c‐Met/VEGFR2 signalling by foretinib improves antitumour effects of nanoparticle paclitaxel in gastric cancer models

Elevated expression of multiple growth factors and receptors including c‐Met and VEGFR has been reported in gastric adenocarcinoma (GAC) and thus provides a potentially useful therapeutic target. The therapeutic efficacy of foretinib, a c‐Met/VEGFR2 inhibitor, was determined in combination with nano...

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Detalles Bibliográficos
Autores principales: Grojean, Meghan, Schwarz, Margaret A., Schwarz, Johann R., Hassan, Sazzad, von Holzen U, Zhang, Changhua, Schwarz, Roderich E., Awasthi, Niranjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178268/
https://www.ncbi.nlm.nih.gov/pubmed/33939252
http://dx.doi.org/10.1111/jcmm.16362