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mGPDH Deficiency leads to melanoma metastasis via induced NRF2
Oxidative stress critically influences carcinogenesis and the progression of melanoma, and aggressive malignant melanoma activity is due to its high metastatic ability. Some findings in several cancer cell lines have indicated that mGPDH, a component of the mitochondrial respiratory chain, also modu...
Autores principales: | Li, Xing, Zhou, Ling, Zhang, Yiming, He, Xuan, Lu, Hao, Zhang, Linlin, Tian, Yongfeng, Liu, Xiufei, Zheng, Hongting, Shao, Jiaqing, Long, Min |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178277/ https://www.ncbi.nlm.nih.gov/pubmed/33939274 http://dx.doi.org/10.1111/jcmm.16542 |
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