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Inhibition of epithelial–mesenchymal transition in retinal pigment epithelial cells by a retinoic acid receptor-α agonist
Epithelial–mesenchymal transition (EMT) in retinal pigment epithelial (RPE) cells plays a key role in proliferative retinal diseases such as age-related macular degeneration by contributing to subretinal fibrosis. To investigate the potential role of retinoic acid receptor-α (RAR-α) signaling in thi...
Autores principales: | Kobayashi, Yuka, Tokuda, Kazuhiro, Yamashiro, Chiemi, Higashijima, Fumiaki, Yoshimoto, Takuya, Ota, Manami, Ogata, Tadahiko, Ashimori, Atsushige, Hatano, Makoto, Kobayashi, Masaaki, Uchi, Sho-Hei, Wakuta, Makiko, Kimura, Kazuhiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178299/ https://www.ncbi.nlm.nih.gov/pubmed/34088917 http://dx.doi.org/10.1038/s41598-021-90618-4 |
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