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Cancer-secreted exosomal miR-21-5p induces angiogenesis and vascular permeability by targeting KRIT1

Cancer-secreted exosomes are critical mediators of cancer-host crosstalk. In the present study, we showed the delivery of miR-21-5p from colorectal cancer (CRC) cells to endothelial cells via exosomes increased the amount of miR-21-5p in recipient cells. MiR-21-5p suppressed Krev interaction trapped...

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Detalles Bibliográficos
Autores principales:	He, Qinglian, Ye, Aihua, Ye, Weibiao, Liao, Xiaomin, Qin, Guoqiang, Xu, Yongqiang, Yin, Yuting, Luo, Huanqian, Yi, Muhua, Xian, Liying, Zhang, Shihao, Qin, Xiyuan, Zhu, Wei, Li, Yuling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178321/ https://www.ncbi.nlm.nih.gov/pubmed/34088891 http://dx.doi.org/10.1038/s41419-021-03803-8

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