Cargando…

Investigation of the mechanisms of VEGF-mediated compensatory lung growth: the role of the VEGF heparin-binding domain

Morbidity and mortality for neonates with congenital diaphragmatic hernia-associated pulmonary hypoplasia remains high. These patients may be deficient in vascular endothelial growth factor (VEGF). Our lab previously established that exogenous VEGF164 accelerates compensatory lung growth (CLG) after...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Lumeng J., Ko, Victoria H., Dao, Duy T., Secor, Jordan D., Pan, Amy, Cho, Bennet S., Mitchell, Paul D., Kishikawa, Hiroko, Bielenberg, Diane R., Puder, Mark
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178332/ https://www.ncbi.nlm.nih.gov/pubmed/34088930 http://dx.doi.org/10.1038/s41598-021-91127-0

Ejemplares similares

A paradoxical method to enhance compensatory lung growth: Utilizing a VEGF inhibitor
por: Dao, Duy T., et al.
Publicado: (2018)

Intranasal delivery of VEGF enhances compensatory lung growth in mice
por: Dao, Duy T., et al.
Publicado: (2018)

Direct thrombin inhibitors as alternatives to heparin to preserve lung growth and function in a murine model of compensatory lung growth
por: Tsikis, Savas T., et al.
Publicado: (2022)

Vascular Endothelial Growth Factor Accelerates Compensatory Lung Growth by Increasing Alveolar Units
por: Dao, Duy T., et al.
Publicado: (2018)

Discovery of pan-VEGF inhibitory peptides directed to the extracellular ligand-binding domains of the VEGF receptors
por: Michaloski, Jussara S., et al.
Publicado: (2016)

Production of Soluble Human Vascular Endothelial Growth Factor VEGF-A(165)-Heparin Binding Domain in Escherichia coli
por: Seyedarabi, Arefeh, et al.
Publicado: (2013)

Dalteparin, a low-molecular-weight heparin, promotes angiogenesis mediated by heparin-binding VEGF-A in vivo
por: NORRBY, KLAS, et al.
Publicado: (2010)

A medium-chain fatty acid analogue prevents hepatosteatosis and decreases inflammatory lipid metabolites in a murine model of parenteral nutrition-induced hepatosteatosis
por: Cho, Bennet S., et al.
Publicado: (2023)

Heparin-Induced Changes of Vascular Endothelial Growth Factor (VEGF(165)) Structure
por: Nemashkalova, Ekaterina L., et al.
Publicado: (2023)

Free Fatty Acid Receptors as Mediators and Therapeutic Targets in Liver Disease
por: Secor, Jordan D., et al.
Publicado: (2021)

Biophysical Studies of the Induced Dimerization of Human VEGF Receptor 1 Binding Domain by Divalent Metals Competing with VEGF-A
por: Gaucher, Jean-François, et al.
Publicado: (2016)

Heparin-binding VEGFR1 variants as long-acting VEGF inhibitors for treatment of intraocular neovascular disorders
por: Xin, Hong, et al.
Publicado: (2021)

PR1P, a VEGF-stabilizing peptide, reduces injury and inflammation in acute lung injury and ulcerative colitis animal models
por: Adini, Avner, et al.
Publicado: (2023)

Binding of VEGF-A is sufficient to abrogate the disturbing effects of VEGF-B together with VEGF-A on retinal endothelial cells
por: Deissler, Heidrun L., et al.
Publicado: (2015)

Computational Modeling of Interacting VEGF and Soluble VEGF Receptor Concentration Gradients
por: Hashambhoy, Yasmin L., et al.
Publicado: (2011)

VEGF heparinized-decellularized adipose tissue scaffolds enhance tissue engineering vascularization in vitro
por: Song, Mei, et al.
Publicado: (2018)

N-VEGF, the Autoregulatory Arm of VEGF-A
por: Katsman, Marina, et al.
Publicado: (2022)

VEGF(121)b and VEGF(165)b are weakly angiogenic isoforms of VEGF-A
por: Catena, Raúl, et al.
Publicado: (2010)

Miniaturizing VEGF: Peptides mimicking the discontinuous VEGF receptor-binding site modulate the angiogenic response
por: De Rosa, Lucia, et al.
Publicado: (2016)

Expression of VEGF(xxx)b, the inhibitory isoforms of VEGF, in malignant melanoma
por: Pritchard-Jones, R O, et al.
Publicado: (2007)

The Presence of VEGF Receptors on the Luminal Surface of Endothelial Cells Affects VEGF Distribution and VEGF Signaling
por: Stefanini, Marianne O., et al.
Publicado: (2009)

An experimental study of VEGF induced changes in vasoactivity in pig retinal arterioles and the influence of an anti-VEGF agent
por: Su, Er-Ning, et al.
Publicado: (2012)

Efficient activation of the lymphangiogenic growth factor VEGF-C requires the C-terminal domain of VEGF-C and the N-terminal domain of CCBE1
por: Jha, Sawan Kumar, et al.
Publicado: (2017)

The Effect of Heparin-VEGF Multilayer on the Biocompatibility of Decellularized Aortic Valve with Platelet and Endothelial Progenitor Cells
por: Ye, Xiaofeng, et al.
Publicado: (2013)

Binding and neutralization of vascular endothelial growth factor (VEGF) and related ligands by VEGF Trap, ranibizumab and bevacizumab
por: Papadopoulos, Nicholas, et al.
Publicado: (2012)

The era of anti-vascular endothelial growth factor (VEGF) drugs in ophthalmology, VEGF and anti-VEGF therapy
por: Pożarowska, Dorota, et al.
Publicado: (2016)

VEGF, VEGF165b and EG-VEGF expression is specifically related with hormone profile in pituitary adenomas
por: Corlan, Ana Silvia, et al.
Publicado: (2019)

Proteolytic Cleavages in the VEGF Family: Generating Diversity among Angiogenic VEGFs, Essential for the Activation of Lymphangiogenic VEGFs
por: Künnapuu, Jaana, et al.
Publicado: (2021)

VEGF and VEGFR2 bind to similar pH-sensitive sites on fibronectin, exposed by heparin-mediated conformational changes
por: Usuelli, Mattia, et al.
Publicado: (2021)

Cancer-derived small extracellular vesicles promote angiogenesis by heparin-bound, bevacizumab-insensitive VEGF, independent of vesicle uptake
por: Ko, Song Yi, et al.
Publicado: (2019)

Aflibercept (VEGF Trap-eye): the newest anti-VEGF drug
por: Stewart, Michael W
Publicado: (2012)

Phytochemicals Targeting VEGF and VEGF-Related Multifactors as Anticancer Therapy
por: Parveen, Amna, et al.
Publicado: (2019)

Controlled release of chitosan/heparin nanoparticle-delivered VEGF enhances regeneration of decellularized tissue-engineered scaffolds
por: Tan, Qi, et al.
Publicado: (2011)

In vivo vascularization of MSC-loaded porous hydroxyapatite constructs coated with VEGF-functionalized collagen/heparin multilayers
por: Jin, Kai, et al.
Publicado: (2016)

Complexation of CXCL12, FGF-2 and VEGF with Heparin Modulates the Protein Release from Alginate Microbeads
por: Adrian, Edyta, et al.
Publicado: (2021)

Migration-promoting role of VEGF-C and VEGF-C binding receptors in human breast cancer cells
por: Timoshenko, A V, et al.
Publicado: (2007)

Where is VEGF in the body? A meta-analysis of VEGF distribution in cancer
por: Kut, C, et al.
Publicado: (2007)

Plasmin Activates the Lymphangiogenic Growth Factors VEGF-C and VEGF-D
por: McColl, Bradley K., et al.
Publicado: (2003)

Compartment Model Predicts VEGF Secretion and Investigates the Effects of VEGF Trap in Tumor-Bearing Mice
por: Finley, Stacey D., et al.
Publicado: (2013)

VEGF(165)b, an antiangiogenic VEGF-A isoform, binds and inhibits bevacizumab treatment in experimental colorectal carcinoma: balance of pro- and antiangiogenic VEGF-A isoforms has implications for therapy
por: Varey, A H R, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_iis3jm3su9gik4a4logko6d5o9