A novel, multitargeted endogenous metabolic modulator composition impacts metabolism, inflammation, and fibrosis in nonalcoholic steatohepatitis-relevant primary human cell models

Nonalcoholic steatohepatitis (NASH) is a complex metabolic disease of heterogeneous and multifactorial pathogenesis that may benefit from coordinated multitargeted interventions. Endogenous metabolic modulators (EMMs) encompass a broad set of molecular families, including amino acids and related met...

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Detalles Bibliográficos
Autores principales: Daou, Nadine, Viader, Andreu, Cokol, Murat, Nitzel, Arianna, Chakravarthy, Manu V., Afeyan, Raffi, Tramontin, Tony, Marukian, Svetlana, Hamill, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178416/
https://www.ncbi.nlm.nih.gov/pubmed/34088912
http://dx.doi.org/10.1038/s41598-021-88913-1

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